Title:
19-NOR-C3,3-DISUBSTITUTED C21-AZACYCLO-SUBSTITUTED STEROID AND METHOD FOR USING SAME
Document Type and Number:
WIPO Patent Application WO/2023/237097
Kind Code:
A1
Abstract:
The present invention provides a 19-nor-C3,3-disubstituted C21-azacyclo-substituted steroid and a method for using same. In particular, the present invention relates to a compound represented by general formula (I), a method for preparing same, a pharmaceutical composition containing the compound, and use thereof as a GABAAR positive allosteric modulator in prevention and/or treatment of various CNS-related diseases, such as treatment of sleep disorder, mood disorder, insomnia, anxiety, depression, traumatic brain injury (TBI), stress and epilepsy, etc. Substituents in the general formula (I) are defined the same as in the description.
Inventors:
TIAN JINGWEI (CN)
MA MINGXU (CN)
YE LIANG (CN)
LI CHUNMEI (CN)
XU HENGWEI (CN)
WANG WENYAN (CN)
ZHANG RUI (CN)
MA MINGXU (CN)
YE LIANG (CN)
LI CHUNMEI (CN)
XU HENGWEI (CN)
WANG WENYAN (CN)
ZHANG RUI (CN)
Application Number:
PCT/CN2023/099369
Publication Date:
December 14, 2023
Filing Date:
June 09, 2023
Export Citation:
Assignee:
SHANDONG LUYE PHARMACEUTICAL CO LTD (CN)
International Classes:
C07J43/00; A61K31/58; A61P25/00
Domestic Patent References:
| WO2021113068A1 | 2021-06-10 | |||
| WO2020150210A1 | 2020-07-23 | |||
| WO2013056181A1 | 2013-04-18 |
Foreign References:
| US20160083417A1 | 2016-03-24 | |||
| US20140018312A1 | 2014-01-16 | |||
| US20170037079A1 | 2017-02-09 | |||
| US5466815A | 1995-11-14 |
Download PDF:
Previous Patent: FOLDING APPARATUS AND TERMINAL DEVICE
Next Patent: NECKBAND, AND BONE CONDUCTION HEADPHONE
Next Patent: NECKBAND, AND BONE CONDUCTION HEADPHONE