Title:
SUGAR-SUBSTITUTED 2-AZETIDINONE USEFUL AS HYPOCHOLESTEROLEMIC AGENT
Document Type and Number:
Japanese Patent JP2009132745
Kind Code:
A
Abstract:
To provide a method for lowering plasma cholesterol level.
The invention relates to sugar-substituted 2-azetidinones having an aryl or substituted aryl group as a substituent at the 1-position and having a hydroxy-substituted phenyl group, especially a 4-hydroxyphenyl group, at the 4-position. The invention also relates to the method for administering the compound of an effective amount for hypocholesterolemia to a mammal in need of such treating.
Inventors:
GHOSAL ANIMA (US)
ZBAIDA SHMUEL (US)
CHOWDHURY SWAPAN K (US)
IANNUCCI ROBERT M (US)
FENG WENQING (US)
ALTON KEVIN B (US)
PATRICK JAMES E (US)
DAVIS HARRY R (US)
ZBAIDA SHMUEL (US)
CHOWDHURY SWAPAN K (US)
IANNUCCI ROBERT M (US)
FENG WENQING (US)
ALTON KEVIN B (US)
PATRICK JAMES E (US)
DAVIS HARRY R (US)
Application Number:
JP2009075266A
Publication Date:
June 18, 2009
Filing Date:
March 25, 2009
Export Citation:
Assignee:
SCHERING CORP (US)
International Classes:
C07H15/26; A61K31/366; A61K31/397; A61K31/70; A61K31/7052; A61K45/00; A61K45/06; A61P3/06; A61P9/10; C07D205/08; A61K31/00
Domestic Patent References:
| JPH08509989A | 1996-10-22 |
Foreign References:
| WO2001027132A1 | 2001-04-19 | |||
| US5756470A | 1998-05-26 |
Other References:
JPN6008043581; Ｂｉｏｏｒｇａｎｉｃ ＆ Ｍｅｄｉｃｉｎａｌ Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ ８, 1998, ３１３-３１８
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita