Title:
Morpholine spirocyclic piperidine amide as a modulator of an ion channel
Document Type and Number:
Japanese Patent JP6088443
Kind Code:
B2
Abstract:
The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
Inventors:
Hadida Rua, Sara Sabina
Vinci, Hailey Marie
Denino, Michael Paul
Fanning, Rev Tyler Duey
Freeman, Brian A.
Gluten Huy, Peter Dedrick Jean
Hillgraph, nicole
Joshi, Pramod
Karel, Edward Adam
Pontiro, Joseph
Serena, arena
Seth, Urby Jagdishby
Harley, dennis james
Alum Gum, Vijayalakusumi
Mirror,mark thomas
Vinci, Hailey Marie
Denino, Michael Paul
Fanning, Rev Tyler Duey
Freeman, Brian A.
Gluten Huy, Peter Dedrick Jean
Hillgraph, nicole
Joshi, Pramod
Karel, Edward Adam
Pontiro, Joseph
Serena, arena
Seth, Urby Jagdishby
Harley, dennis james
Alum Gum, Vijayalakusumi
Mirror,mark thomas
Application Number:
JP2013558104A
Publication Date:
March 01, 2017
Filing Date:
March 13, 2012
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D498/10; A61K31/5386; A61P1/00; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P5/00; A61P7/06; A61P9/00; A61P9/06; A61P9/12; A61P11/02; A61P13/02; A61P13/10; A61P13/12; A61P19/00; A61P19/02; A61P25/00; A61P25/06; A61P25/08; A61P25/18; A61P25/22; A61P25/24; A61P29/00; A61P43/00
Domestic Patent References:
| JP11512723A | ||||
| JP2006512404A |
Foreign References:
| WO2011092198A1 | ||||
| WO2010151595A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Natsuki Morishita