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Document Title |
JPH05292981A |
PURPOSE: To obtain a powdery phospholipid having high purity in high yield by carrying out a base-interchange reaction with phospholipase D originated from microorganism of the genus Streptomyces and a crystallization process under respe...
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JPH0573390B2 |
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JPH0571236B2 |
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JPH05236974A |
PURPOSE: To selectively introduce a fatty acid into the Sn2-position by adding glycerol in relation to the synthesis of a phospholipid. CONSTITUTION: The objective method for producing a phospholipid having high physiological activity wi...
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JPH0560357B2 |
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JPH05222050A |
PURPOSE: To prepare the subject new compound which has squalene synthetase inhibitory activity and is useful for treating hypercholesterolemia, etc. CONSTITUTION: The new inhibitor is a compound represented by the formula. Such a compoun...
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JPH0542917B2 |
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JPH05123179A |
PURPOSE: To obtain the subject new compound useful as pharmaceuticals active to induce the production of a hematopoietic colony stimulating factor and having antimycotic action, carcinostatic action, etc., by culturing a microbial strain...
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JPH05123176A |
PURPOSE: To obtain the subject compound useful for foods, cosmetics, pharmaceuticals, etc., on an industrial scale at a low cost by culturing a microbial strain of genus Escherichia, etc., in a medium incorporated with oil and fat contai...
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JPH0591866A |
PURPOSE: To obtain the subject microorganism capable of efficiently producing protochlorophyllide by introducing a DNA containing a broken frxC gene originated from a microorganism belonging to the genus Plectonema, etc., into a host mic...
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JPH05501497A |
Improved process for enzymatic interesterification of a phospholipid with a fatty acid or ester is obtained by using an enzyme immobilized by adsorption on a particulate macroporous carrier.
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JPH0517918B2 |
Lysophospholipids-containing phospholipids with reduced neutral lipids content can be produced by a process which comprises subjecting neutral lipids- and lysophospholipids-containing phospholipids to treatment with acetone in the presen...
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JPH05501057A |
Specific exchange of the acyl group in the sn-2 position of a phospholipid is achieved by reacting it with a free fatty acid in the presence of an extracellular phospholipase A2.
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JPH0549488A |
PURPOSE: To efficiently obtain lysophospholipid useful for medical surfactant, etc., having high emulsion stability by dissolving an animal- or vegetable-derived phospholipid in a nonpolar organic solvent, adding water to the solution to...
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JPH0515719B2 |
A pharmaceutical composition containing as a pharmaceutically active ingredient at least one isomer of inositol triphosphate (IP3) in an amount sufficient to reduce the negative effect of cadmium or aluminium in the body or inhibit or re...
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JPH05398B2 |
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JPH0481431B2 |
PURPOSE:To obtain a lecithin having excellent emulsifiability and having sufficiently safe and excellent quality to be used as food additive, by carrying out the enzymatic treatment of lecithin in the presence of a specific compound capa...
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JPH04360690A |
PURPOSE: To inexpensively and simply obtain the title compound useful in the field of drug, cosmetic, food, etc., by providing lipase with a limit amount of water required for manifestation of activity of lipase and acylating hydroxyl gr...
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JPH04356192A |
PURPOSE: To simultaneously carry out plural reactions such as exchange reaction or hydrolytic reaction of a phospholipid and obtain a modified phospholipid in high yield at a low cost by reacting specific dried microbial cells with a raw...
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JPH04356191A |
PURPOSE: To obtain a phospholipid in high yield at a low cost with excellent productivity by bringing microbial cells having a lipolytic enzyme into contact with a raw material phospholipid or the raw material phospholipid and a receptor...
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JPH04335893A |
PURPOSE: To obtain an ester in high efficiency while repeatedly using an enzyme stably over a long period by using an immobilized enzyme produced by adsorbing a fatty acid or its derivative and a lipid decomposition enzyme to an insolubl...
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JPH04505853A |
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.
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JPH04279589A |
PURPOSE: To provide a new squalene synthetase inhibitor effective as a therapeutic agent for the hypercholesterolemia and as an inhibitor for fungus proliferation. CONSTITUTION: The medicinally permissible salts of a compd. of the formul...
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JPH04211387A |
PURPOSE: To obtain new phospholipids and nucleoside derivatives in one stage by carrying out base exchange reaction of phosphatidylcholine with a nitrogen- containing alcohol such as nucleoside or a polyol using phospholipase D-P. CONSTI...
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JPH04148691A |
PURPOSE: To simply obtain the subject phospholipid at a low cost by carrying out ester interchange between a phospholipid and triglycerides with a high content of highly unsaturated fatty acids as a substrate in the presence of a specifi...
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JPH04145088A |
PURPOSE: To obtain the title high-purity compound useful for food industry, drugs, cosmetics, etc., safely, in good productivity and inexpensively without using a solvent by treating crude lecithin with an enzyme in the presence of an ac...
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JPH04108393A |
PURPOSE: To obtain a readily purifiable oleic acid-containing lipid of high purity by culturing a microorganism capable of producing the oleic acid-containing lipid and producing the oleic acid-containing lipid. CONSTITUTION: A new micro...
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JPH0499724A |
PURPOSE: To obtain a new skin drug for external use, especially an emulsified type skin drug for external use excellent in beautifying and whitening effects and preventive effects on aging of the skin by blending at least one of a specif...
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JPH0466091A |
PURPOSE: To enable simple and continuous obtaining of the subject compound in high purity and yield under mild reaction conditions by reacting lecithin with a specific enzyme in the presence of an organic solvent and water. CONSTITUTION:...
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JPH0453493A |
PURPOSE: To efficiently produce the subject ester having an excellent surface-active effect, low in skin irritation and excellent in biodegradability by reacting a phosphoric ester with a polyvalent alcohol in the presence of a specified...
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JPH0420293A |
PURPOSE: To prepare the subject compound, a dimer phospholipid, useful as a material for forming a drug ribosome in a highly good yield by reacting a phosphatidyl compound with a phospholipid in the presence of phospholipase. CONSTITUTIO...
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JPH0368038B2 |
New glycerol-3-phosphoric acid halogenoalkyl esters of the general formula I (I) in which R denotes the radical R1 or an acyl radical -COR1, R1 denotes a straight-chain or branched, saturated or unsaturated alkyl group having 1 to 25 C a...
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JPH0367676B2 |
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JPH0367677B2 |
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JPH0367675B2 |
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JPH0367075B2 |
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JPH0354924B2 |
A pharmaceutical composition containing as a pharmaceutically active ingredient at least one isomer of inositol triphosphate (IP3) in an amount sufficient to reduce the negative effect of cadmium or aluminium in the body or inhibit or re...
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JPH03160994A |
PURPOSE: To enable continuous production of an emulsifier having excellent performance in high efficiency by reacting a phospholipid with a hydroxyl- containing compound in the presence of a phospholipase D having phosphatidyl group tran...
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JPH0338824B2 |
A pharmaceutical composition containing as a pharmaceutically active ingredient at least one isomer of inositol triphosphate (IP3) in an amount sufficient to reduce the negative effect of cadmium or aluminium in the body or inhibit or re...
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JPH03123493A |
PURPOSE: To produce a monoacylglyceroline lipid in a good yield in a mild condition and enable mass production thereof by hydrolyzing a diacylglyceroline lipid such as phosphatidylethanolamine using a respectively specified enzyme and re...
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JPH0398590A |
PURPOSE: To prepare a lisophospholipid capable of being readily purified in a good yield by treating a natural phospholipid, etc., with one or more enzymes selected from a group of phospholipase A2, etc., in a nonionic non-polar organic ...
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JPH0387191A |
PURPOSE: To obtain the subject compound useful as an emulsifier to be used in the fields of food, cosmetics, agricultural chemicals, marine product industry, etc., and an emulsifier and liposome-forming substrate in pharmaceutical field ...
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JPH0324018A |
PURPOSE: To obtain a lipid metabolic improver, containing microbial dell lipids of a marine microorganism having the ability to produce eicosapentaenoic acid and/or the aforementioned microbial cells as an active ingredient and capable o...
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JPH037233B2 |
A pharmaceutical composition containing as a pharmaceutically active ingredient at least one isomer of inositol triphosphate (IP3) in an amount sufficient to reduce the negative effect of cadmium or aluminium in the body or inhibit or re...
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JPH0322991A |
PURPOSE: To obtain the subject glycerol useful as an emulsifier for food, etc., in high purity at a low cost by treating lecithin with a specific phospholipase D in the presence of glycerol, concentrating and drying the obtained reaction...
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JPH02295992A |
PURPOSE: To economically and specifically extract, recover and obtain phosphatidylinositol useful as a reagent for research by purifying a phospholipid from phosphatidylinositol-containing raw material phospholipid using methanol. CONSTI...
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JPH02283283A |
PURPOSE: To obtain the title composition capable of producing ascorbic acid-2- phosphate efficiently and stably from ascorbic acid and a phosphoric acid donor, comprising a solution containing an enzyme showing activity of forming ascorb...
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JPH02502096A |
An invention relating to novel compounds and compositions of matter for use in alleviating the symptoms of a number of diseases, especially those caused by viral infection of mammals, including humans, is disclosed. Compositions of the p...
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JPH02138985A |
PURPOSE: To obtain a lipid ingredient containing a fatty acid and a derivative thereof which are melanization inhibitory substances from a cell proliferated by proliferating an established cell of a warm-blooded animal and use the result...
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JPH0216319B2 |
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