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JP5756137B2 |
The present invention provides a method for extracting lipids from microorganisms without using a nonpolar organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microo...
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JP2015133969A |
To provide a process for extracting, recovering, isolating or obtaining lipids from microorganisms.The present invention provides a method for extracting lipids from microorganisms without using a nonpolar organic solvent as an extractio...
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JP5752675B2 |
The present invention relates to a method of producing a phytosterol ester and/or a phytostanol ester comprising: a) admixing a phospholipid composition comprising at least between about 10% to about 70% plant phospholipid and at least a...
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JP5722536B2 |
The present invention provides a method for extracting lipids from microorganisms without using a nonpolar organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microo...
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JP2015082970A |
To provide a method for producing a Panax ginseng effective ingredient which decomposes Rb1 contained in Panax ginseng extract as an ingredient into an effective ingredient through the decomposition route to Rd, and does not decomposes t...
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JP5684989B2 |
To provide a composition originated from Dioscorea esculenta rhizome richly containing diosgenin glycoside useful in the fields of foods, medicines, and cosmetics, to provide a method for efficiently producing the composition, and to pro...
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JP5670310B2 |
A fungus (A) that can produce cholesterol (I) autonomously, is new. Independent claims are also included for: (1) production of (I) by culturing (A); (2) production of (I) or its metabolic intermediates or a mixture of sterols labeled by...
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JP5646168B2 |
Disclosed is a means for improving the poor conversion efficiency in a conventional bioconversion system using a transformant which is given by introducing a gene originated from xerogenic organisms. A transformant is prepared by using a...
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JP5646992B2 |
The present invention refers to new crystalline forms of cortexolone 17α-propionate and their pharmaceutical use.
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JP5553956B2 |
Strain (A) of microorganism that includes a deletion of at least one of the genes udhA, qor and/or pgi, provided that if (A) is a bacterium at least one of udhA and qor is deleted. Independent claims are also included for the following: ...
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JP5506403B2 |
A proliferation promoting agent for neural stem cells, which comprises a compound produced by Penicillium sp. CND1007 (FERM BP-10917) or a pharmaceutically acceptable salt thereof, as an active ingredient; a novel compound produced by Pe...
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JP5461082B2 |
To provide a compound having anticancer activities and antibacterial activities.The new microorganism produces the new compound represented by formula (I). The anticancer agent, the infiltration inhibitor of the surrounding tissue of a c...
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JP2014050357A |
To provide a production method of a fermentation product containing the hydroxide of glycyrrhetinic acid which effectively and easily produces a fermentation product containing the hydroxide of glycyrrhetinic acid from glycyrrhizin, a pr...
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JP5349846B2 |
To provide a method for efficiently producing 1α,25-dihydroxyvitamin D using a transformant capable of efficiently transforming a vitamin D into 1α,25-dihydroxyvitamin D compared to conventional enzymes. The method for producing 1α,25...
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JP5294509B2 |
This invention provides a method for preparing cycloastragenol monoglucoside CMG (cydoastragenol-6-O-²-D-glucoside), comprising the steps of: a. using astragaloside IV or Astragali extracts prepared by a conventional method as raw mater...
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JP5231777B2 |
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JP2013511973A |
The present invention relates to a novel 7β-hydroxysteroid dehydrogenase obtained from Collinsella bacteria, especially Collinsella aerofaciens strain, a sequence encoding the enzyme, a method for producing the enzyme, and enzymatic con...
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JP5113832B2 |
A process for the enantioselective reduction of compounds having a steroid structure (ABCD) including one or several heteroatoms, one or several double bonds and/or aromatic components in the ring structure and having at least one oxo gr...
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JP2012239412A |
To provide a gene for coding an enzyme that reduces the position 24 of a steroid skeleton, and a method for producing steroids and vitamin D3.Disclosed are an enzymatic conversion method for reducing the double bond at the 24 position of...
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JP5053838B2 |
A fungus (A) that can produce cholesterol (I) autonomously, is new. Independent claims are also included for: (1) production of (I) by culturing (A); (2) production of (I) or its metabolic intermediates or a mixture of sterols labeled by...
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JPWO2010095721A1 |
An object of the present invention is to provide a P450 monooxygenase system having heat resistance and organic solvent resistance. Another object of the present invention is to provide a method for producing an oxide in a high temperatu...
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JP4998957B2 |
A vitamin D 3 hydroxylase is purified from Pseudonocardia autotrophica cell, and a primer is designed based on amino acid sequence obtained from hydroxylase. Subsequently, PCR is conducted using genomic DNA of Pseudonocardia autotrophica...
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JPWO2010079594A1 |
An object of the present invention is to obtain a highly active P450scc enzyme protein for the P450scc enzyme protein, which is an important enzyme protein that catalyzes the first stage of industrially useful steroid hormone biosynthesi...
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JP4953547B2 |
The invention relates to ginsenoside glycosidases which hydrolyzes ginsenosides having higher contents in ginsengs so as to prepare rare ginsenosides with high physioloigical activity. Said ginsenoside glycosidases are derived from micro...
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JP2012060974A |
To provide a method for artificially culturing a mushroom, which uses coffee extracted grounds as the main raw material of a culture medium (mushroom bed), and to provide a method for producing a ganoderenic acid compound, comprising sep...
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JP2012024084A |
To provide a method of efficiently producing Δ5,7-sterol of cholesta-5,7,24-trien-3β-ol or the like and hydrocortisone.The Δ5,7-sterol and the hydrocortisone are produced using a yeast modified so that the expression of an acyl-CoA: s...
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JP4864277B2 |
The present invention relates to novel yeast strains, methods and genetic constructs for their preparation, and their use for the synthesis or modification of steroidal compounds. More particularly, the invention describes strains having...
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JP4845393B2 |
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JP2011526481A |
12alpha -Hydroxysteroid dehydrogenase (12alpha -HSDH), obtained from Clostridium sp.and having a molecular weight of 27-30 kD, is new. Independent claims are included for: (1) 12alpha -HSDH-mutant with a modified cosubstrate-utilization;...
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JP4769868B2 |
The present invention relates to a method of producing corosolic acid by using plant cells that produce corosolic acid. More particularly, the present invention relates to a method of producing corosolic acid by using plant cell suspensi...
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JP2011517945A |
A method for reducing the amount of cholesterol and/or improving the texture and/or reducing weight loss and/or increasing the fat stability of a meat based food product comprising: a) contacting meat with a lipid acyltransferase; b) inc...
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JP2011115078A |
To provide a method for efficiently producing a hydroxylated vitamin D derivative while suppressing the side reaction in the hydroxylation reaction of vitamin Ds by modifying a hydroxylase such as Vdh-K1 structurally associated with Vdh ...
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JP4699661B2 |
A process for the preparation of desglucodesrhamnoruscin which comprises the hydrolysis of Ruscus Aculeatus steroid glycosides (ruscosaponins) through fermentation of a substrate containing said glycosides by means of fungi of the asperg...
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JP4668176B2 |
Soyasapogenol B is biosynthesized via two steps of hydroxylation reaction of its precursor ²-amyrin. However, the gene of the hydroxylase concerned in this reaction has not been revealed. Therefore, it was impossible to apply a genetic ...
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JP2011024534A |
To solve a problem in that soyasapogenol B is bio-synthesized by the ring closure of 2,3-oxidosqualene produced from β-amyrin which is a bio-synthetic precursor of the soyasapogenol B, through a mevalonic acid pathway and further throug...
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JP4621468B2 |
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JP4620932B2 |
The present invention relates to genetically modified yeast strains autonomously producing, from a simple carbon source, steroids. The invention also relates to a method for producing steroids from such yeast strains.
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JP4606523B2 |
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JP4603220B2 |
A process for the preparation of desglucodesrhamnoruscin which comprises the enzymatic hydrolysis of Ruscus Aculeatus steroid glycosides (ruscosaponins) by means of crude hydrolases from aspergillus niger.
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JP4571862B2 |
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JP2010531660A |
The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by the bioconversion of compound...
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JP4549625B2 |
Disclosed herein is nanoemulsion prepared by emulsifying main metabolites of ginseng saponin obtained by conversion of glucose, i.e. compound K (20-O- beta -D-glucopyranosyl-20(S)-protopanaxadiol), ginsenoside F1 (20-O- beta -D-glucopyra...
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JP4548849B2 |
To control the differentiation of mesenchymal stem cells into steroid hormone producing cells. Mesenchymal stem cells can be differentiated into steroid hormone-producing cells by being stimulated by a transcriptional factor (SF-1), pref...
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JP4545255B2 |
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JP2010193809A |
To provide a method for producing a feeding center-suppressing substance.The method for producing the feeding center-suppressing substance comprises a step of fermenting a caralluma fruit and caffeine with lactobacillus. The feeding cent...
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JP4537887B2 |
The present invention provides a method for extracting lipids from microorganisms without using a nonpolar organic solvent as an extraction solvent. In particular, the present invention provides a method for extracting lipids from microo...
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JP2003501045T6 |
A manufacturing method of デスグルコデスラムノラシン including hydrolysis of the glycoside through fermentation by a fungus Aspergillus niger kind of a substrate containing a Ruscus aculeatus steroid glycoside (Lascaux sapon...
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JP2003501044T6 |
A manufacturing method of デスグルコデスラムノラシン which uses crude hydrolase of Aspergillus niger origin and including enzymatic hydrolysis of a Ruscusaculeatus steroid glycoside (Lascaux saponin).
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JP4467722B2 |
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JP4460300B2 |
Es wird ein Verfahren zur Überexpression von Dehydrogenasen, besonders zur Überexpression von DELTA1-Dehydrogenasen, insbesondere zur Überexpression von 3-Ketosteroid-DELTA1-Dehydrogenasen, sowie die für die Überexpression verwendba...
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