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WO/2018/191701A1 |
Provided herein are methods for screening biological functions of microscale biological systems comprises segregating each microscale biological system from a set of microscale biological systems to be screened into individual discrete v...
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WO/2018/187752A1 |
Provided herein are methods for the controlled, independent modification of the surface of titanium-based materials and compositions generated thereby. The methods allow for the alteration of multiple surface characteristics including ge...
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WO/2018/186185A1 |
This cell cultivation method includes a step in which kidney cells 24 are cultivated in an unadhered condition in a culture vessel 26 for a period of five days or more, an aggregate 30 of the kidney cells 24 is formed during the cultivat...
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WO/2018/174748A1 |
The invention relates to the field of biotechnology and pharmaceutics. Proposed is a method for ultra-high performance screening of biological objects which is based on microfluidic generation of droplets of a biocompatible water-in-oil-...
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WO/2018/169972A1 |
Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 1,4-BDO are disclosed. For example, genetically modified methanotrophs that are capable of generating 1,4-BDO at high t...
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WO/2018/161631A1 |
An enzymatic deacidification method for partial glyceride lipase and PUFA-rich oil, comprising the following steps: 1) mixing a polyunsaturated fatty acid (PUFA)-rich oil with a non-polar organic solvent and a short-chain monohydric alco...
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WO/2018/160908A1 |
The present disclosure provides technologies for modulating gene expression.
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WO/2018/159797A1 |
The present invention addresses the problem of providing: an embedding agent for a cell mass or a cell structure which allows the cell mass or the cell structure to be stably transported during transportation at low temperature, and allo...
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WO/2018/155622A1 |
By suppressing the loss of living cells or living tissue during the production of a PVA gel that contains living cells or living tissue, the present invention addresses the problem of supplying a cell- or tissue-embedding device that has...
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WO/2018/151186A1 |
The present invention provides a bead containing a polymer that contains a uronic acid unit having a mercapto group, wherein all or a portion of the mercapto group forms a disulfide bond.
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WO/2018/151423A1 |
The present invention relates to: transparent disk-shaped microparticles surface-modified with polydopamine; and cell culturing using the same. When cells are cultured using disk-shaped microparticles coated with polydopamine according t...
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WO/2018/147630A1 |
The present invention relates to a method for producing a virus by a semi-continuous culture method and a method for mass-producing a fish virus at a high concentration by using a cell line attached to a microcarrier, which overcomes com...
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WO/2018/148054A1 |
A nanobiocatalytic membrane for a filtration system is provided which includes a filtration membrane and a plurality of nanobiocatalyst nanoparticles associated with the membrane, each of the nanobiocatalyst nanoparticles including a cor...
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WO/2018/141071A1 |
The present invention relates to products and method of preparing and using surface modified polymeric material having siliceous particles deposited thereon. The method and article are disclosed wherein a plastic substrate is provided wi...
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WO/2018/144686A1 |
A method for obtaining grey water excreta includes reducing ammonia content of the liquid fraction in a first porous medium in which the ammonia content is decomposed, and reducing the byproducts in a second batch of similar porous mediu...
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WO/2018/140456A1 |
Disclosed are variants of ACE2, pharmaceutical compositions comprising the variants of ACE2, and treatment methods for reducing Angiotensin II (1-8) plasma levels and/or increasing Angiotensin (1-7) plasma levels in a subject in need the...
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WO/2018/135891A1 |
The present invention relates to a three-dimensional cell culturing scaffold comprising mammal-derived mesenchymal stem cells or cells differentiated therefrom in alginate hydrogel, a three-dimensional cell culturing method using the sam...
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WO/2018/122856A1 |
The present invention discloses an electrophoretic chip comprising: (a) a non- conductive substrate designed to support elements of said electrophoretic chip; (b) an electrode structure for conducting current through said electrophoretic...
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WO/2018/123856A1 |
The purpose of the present invention is to provide: a method for easily obtaining a culture supernatant having a reduced amount of unwanted enzymes; a microorganism that can be used in said method; and a method for producing a target sub...
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WO/2018/116297A1 |
Disclosed are various enzymatic processes for the enrichments of oils with omega-3 fatty acids, and specific lipase preparations for use with these processes.
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WO/2018/111967A1 |
Provided herein, in some embodiments, are methods of purifying a nucleic acid preparation. The methods may comprise contacting a nucleic acid preparation comprising messenger ribonucleic acid with an RNase III enzyme that is immobilized ...
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WO/2018/110739A1 |
The present invention provides, as a bacteria slime-based coating material using bacteria capable of forming slime, a coating material comprising an adsorbent on which slime-forming bacteria are adsorbed, and a binder. According to the p...
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WO/2018/103409A1 |
Disclosed are a methylocystis and the use thereof in the selective resolution and preparation of (S)-α-ethyl-2-oxo-1-pyrrolidine acetates. After cell immobilization of the enzyme-producing methylocystis, the methylocystis is applied to ...
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WO/2018/102319A1 |
The present invention provides compositions and methods for producing magnetic bionanocatalysts (BNCs) comprising metabolically self-sufficient systems of enzymes that include P450 monooxygenases or other metabolic enzymes and cofactor r...
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WO/2018/094522A1 |
The present disclosure provides an encapsulated liver tissue that can be used in vivo to improve liver functions, in vitro to determine the hepatic metabolism and/or hepatotoxicity of an agent and ex vivo to remove toxic compounds from p...
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WO/2018/081542A1 |
The invention is directed to compositions, tools and methods for the manufacture of construction materials, masonry, solid structures and compositions to facilitate dust control. More particularly, the invention is directed to the manufa...
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WO/2018/081616A1 |
Disclosed are compositions and methods relating to micromatrices of encapsulated aggregates of pre-differentiated stem cells.
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WO/2018/065887A1 |
The present invention relates to compositions comprising a polymeric matrix or a gel containing functional enzymes capable of re-creating under culture conditions the cell microenvironment existing in vivo. The present invention also rel...
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WO/2018/055588A1 |
A material for reducing the content of polluting and/or unwanted substances in a liquid, comprising at least one polymeric and/or inorganic base, suitable to be immersed in said liquid, having at least a surface, whereto is bonded at lea...
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WO/2018/052054A1 |
The purpose of the present invention is to provide a method for efficiently producing an immobilized allulose epimerase having a high activity and excellent durability. An immobilized allulose epimerase having a high specific activity an...
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WO/2018/046129A1 |
The invention relates to methods for producing hydrogels for reversibly immobilising glycoproteins and/or cells on the hydrogel, involving lectins being coupled to the hydrogel, corresponding lectin-coupled hydrogels, the use thereof in ...
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WO/2018/034877A1 |
The present invention provides compositions and methods for reducing microbial and nematodal contamination or infection in plants, animals, fabrics, and products therefrom. The present invention also provides compositions and methods for...
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WO/2018/028848A1 |
The present invention relates to a method for producing a protein-functionalized film, in which a protein is bound to a copolymer or a polymer having an unhydrolyzed or hydrolyzed thiolactone functionalization is bound to the film by mea...
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WO/2018/021543A1 |
Stem cells can be efficiently proliferated by culturing the stem cells in the presence of a novel recombinant fibronectin fragment.
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WO/2018/015213A1 |
Site-specific modification of proteins with microbial transglutaminase (MTG) is a powerful and versatile strategy for a controlled modification of proteins under physiological conditions. We present evidence that solid-phase microbead- i...
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WO/2018/017845A1 |
Provided herein, in some embodiments, are hydrogel-elastomer and hydrogel-alginate devices, compositions and associated methods to encapsulate living cells.
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WO/2018/004341A1 |
The invention relates to a CLEA comprising magnetizable particles, characterized in that the magnetizable particles comprise particles of a zerovalent metal selected from the group of iron, nickel, cobalt and any mixture thereof, which p...
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WO/2017/220862A1 |
The present invention relates to an active solid state fermentation bioreactor for producing gases, liquid(s) or solids from gaseous or gaseous and liquid starting materials and to a fermentation process using such reactor. The bioreacto...
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WO/2017/212829A1 |
Provided are: a cell culturing method comprising a heating step in which a liquid culture medium having a heating phase transition temperature Tc and a cooling phase transition temperature Tcs that is lower than Tc is heated from less th...
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WO/2017/213871A2 |
Enzyme-immobilizing MOFs and methods for their use in enzymatically catalyzed reactions are provided. The MOFs are channel-type MOFs that present a hierarchical pore structure comprising a first set of large channels sized for enzyme imm...
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WO/2017/208020A2 |
The invention provides a process for producing a gel network, which gel network comprises a plurality of joined gel objects, which process comprises: forming a plurality of gel objects in one or more microfluidic channels; dispensing the...
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WO/2017/207298A1 |
A bifunctional polymer is functionalized at one end with an azlactone end group to conjugate biomolecules of interest, and is functionalized at another end with an azide anchor group to attach the polymer to a substrate. Methods of makin...
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WO/2017/203440A1 |
The present invention relates to a method for producing microbial probiotic biofilms and their uses in the biomedical, industrial, food and environmental field.
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WO/2017/204235A1 |
A three-dimensional structure comprising a plurality of polymer film layers, wherein microparticles are enclosed in the inner space of the three-dimensional structure and the plurality of polymer film layers have mechanical strengths dif...
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WO/2017/199737A1 |
Provided is a method for collecting cultured cells, said method comprising a precipitation step for, after the completion of culture, precipitating cultured cells from a cultured cell dispersion in a single culture container, wherein: th...
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WO/2017/191093A1 |
The invention relates to a method for coating microorganisms, preferably probiotic microorganisms, and to a powder of said coated microorganisms, obtained using said method, as well as to compositions comprising said powder.
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WO/2017/188161A1 |
This flavor improving material includes, as an active ingredient, a partial hydrolyzate of animal/plant fats and oils that has come into contact with an adsorbent. The pH of the adsorbent is preferably 3.0-8.0 and silica gel is preferabl...
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WO/2017/186864A1 |
The invention provides an improved process for producing β-lactam antibiotics catalyzed by an enzyme, which is immobilized onto a carrier, wherein the resulting β-lactam antibiotics are poorly soluble in the reaction media. The process...
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WO/2017/178523A1 |
The present invention relates to a process for the production of a dyed fabric using enzyme aggregates. In particular, the process of the invention comprises a step of providing a woven fabric that comprises a base layer and an additiona...
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WO/2017/180383A1 |
The present invention provides magnetic macroporous polymeric hybrid scaffolds for supporting and enhancing the effectiveness of bionanocatalysts (BNC). The novel scaffolds comprise cross-linked water-insoluble polymers and an approximat...
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