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WO/2018/109348A1 |
The present invention relates to a novel method for preparing surfactant compositions made from alkyl-L-iduronamides, alkyl-L-rhamnosides and alkyl-D-glucuronamides, the compositions obtained by said method and the uses thereof.
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WO/2018/102447A2 |
The invention relates to a process for producing food ingredients from Stevia rebaudiana plant and their use in food products, beverages and other consumables. Obtained compositions are useful as flavors, sweeteners, antioxidants, and ot...
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WO/2018/101434A1 |
The present invention addresses the problem of providing a glycosylated chlorin e6 derivative which has excellent tumor cell-killing properties (phototoxic property) and growth-inhibiting effect on tumor tissues and which is used for pho...
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WO/2018/100560A1 |
The present invention concerns Au and Cu-based mononuclear coordination compounds, drug formulations thereof, the relating synthesis and encapsulation method in macromolecules or supramolecular aggregates or nanostructures, as well as th...
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WO/2018/100561A1 |
The present invention relates to mononuclear coordination compounds of Au and Cu, pharmaceutical formulations based thereof, the relative method of synthesis and encapsulation of the compounds in macromolecules, supramolecular aggregates...
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WO/2018/100562A1 |
The present invention relates to mononuclear and dinuclear coordination compounds of Ru and Ga, pharmaceutical formulations based thereof, the relative method of synthesis and encapsulation of the compounds in macromolecules, supramolecu...
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WO/2018/098342A1 |
The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed.
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WO/2018/095975A1 |
The invention relates to the use of a triacylated mannosylerythritol lipid as a corrosion inhibitor, to compositions comprising a triacylated mannosylerythritol lipid, and to methods implementing a triacylated mannosylerythritol lipid.
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WO/2018/097239A1 |
The present invention addresses the problem of providing a clearing agent which is capable of, after administering a fusant of a streptavidin mutant with a molecular probe, preventing the localization of the fusant at a target site such ...
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WO/2018/089348A1 |
This disclosure relates to the field of molecules having pesticidal utility against pests in phyla Nematoda, Arthropoda, and/or Mollusca, processes to produce such molecules and intermediates used in such processes, compositions containi...
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WO/2018/083490A2 |
There is provided a molecule comprising a chain of seven or more contiguous units of 4,6-dideoxy-4-acylamido-α-pyranose, each pair of units joined by a C1-C2 or a C1-C3 link, the chain having a terminal end and a reducing end, wherein t...
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WO/2018/075874A1 |
Novel diterpene glycosides isolated from Stevia are provided herein. Compositions and consumables comprising the novel diterpene glycosides are also provided herein. Methods of enhancing the sweetness and/or flavor of consumables using t...
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WO/2018/068090A1 |
The present invention relates generally to the field of glycanics and its application to the generation of glycoconjugates for therapeutic use. The present invention also relates to process for the preparation of glycoconjugates.
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WO/2018/070546A1 |
[Problem] To provide a novel hydrogelator which can be produced by a simple method and contains a monourea compound having a sugar structure. [Solution] This hydrogelator comprises a compound represented by formula (1) below (in the form...
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WO/2018/067683A1 |
Novel diterpene glycosides containing ent-atisene cores are provided herein. Compositions and consumables comprising the novel diterpene glycosides are also provided herein. Methods of enhancing the sweetness and/or flavor of consumables...
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WO/2018/067805A1 |
Disclosed are solid state forms of Sotagliflozin, processes for preparation thereof, and pharmaceutical compositions thereof.
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WO/2018/068010A1 |
Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, highly potent multimeric ...
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WO/2018/067900A1 |
Provided herein are solid phase methods for the synthesis of conjugated oligomeric compounds and intermediates used in such methods. In particular, the solid phase methods provide for addition of a phosphoramidite functionalized conjugat...
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WO/2018/053202A1 |
The disclosure relates to the field of specialty chemicals. In particular, the disclosure provides novel 1,3-fatty-diol compounds of formulae (II) and (IV) and derivatives thereof, in partiuclar gycosides thereof, which are usefule.g.Jn ...
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WO/2018/050099A1 |
Provided is a panaxdiol-type ginsenoside derivative having a structure as shown in formula I or formula II. Also provided is the use thereof in the preparation of a drug for preventing and treating atherosclerosis. The panaxdiol-type gin...
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WO/2018/031585A1 |
The invention describes the extraction method to obtain the highest amount of resveratrol from wasted biomass produced by grapes processing. Resveratrol, which is found rich in the grapes, especially in grape skin and seed, is one of the...
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WO/2018/029272A1 |
A method for purifying rebaudioside M, which method comprises: (a) providing a solution comprising rebaudioside M at a concentration of at least about 10g/L and at a purity of at least about 10% by weight on a dry basis; and (b) crystall...
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WO/2018/030602A1 |
The present invention relates to: a novelly developed butane-tetraol-based amphipathic compound; a preparation method therefor; and a method for extracting, solubilizing, stabilizing, crystallizing, or analyzing membrane proteins by usin...
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WO/2018/029274A1 |
A method for purifying rebaudioside A, which method comprises: (a) providing a solution comprising rebaudioside A; (b) concentrating the said solution; and (c) crystallizing from the solution a high purity composition comprising rebaudio...
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WO/2018/026087A2 |
Compounds of chemical formula 1 or pharmaceutically acceptable salts thereof according to the present invention are sugar-added enclomiphene derivatives that improve bioavailability while maintaining antagonistic activity to estrogen rec...
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WO/2018/021527A1 |
The present invention addresses the problem of providing a method for supplying or maintaining type-17 collagen in a living body. The problem addressed by the present invention is solved by providing a composition having as an active ing...
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WO/2018/020046A1 |
The present invention provides a stable synthetic saccharide of Hib polyribosylribitol- phosphate (PRP) derivative and conjugate thereof. Said saccharide, said conjugate and pharmaceutical compositions thereof are hydrolysis-resistant, l...
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WO/2018/014866A1 |
Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-2-eth
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WO/2018/014111A1 |
There is provided methods, compositions and treatment regimens for treating cancer, or for inhibiting metastasis/recurrence of cancer in a patient using 1) a primary cancer treatment such as chemotherapy, and 2) within 12 to 120 hours po...
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WO/2018/012669A1 |
The present invention relates to a mesitylene-cored amphiphile, a method of preparing the same and a method of extraction, solubilization, stabilization, crystallization or analysis of a membrane protein using the same. When a mesitylene...
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WO/2018/007495A1 |
The present invention relates to compounds of formula (I) and compositions comprising them for use in enhancing umami taste and/ or saltiness of a food product.
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WO/2018/007496A1 |
The present invention relates to compounds and compositions for use in enhancing flavor and/or saltiness of a food product. Particularly, the present invention relates to compounds of the general formula I) and compositions comprising them.
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WO/2018/005324A1 |
Disclosed herein are artificial Invaplexes comprising deacylated lipopolysaccharides and methods of making and using thereof.
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WO/2018/003652A1 |
A compound used in the conventional enzymatic reactions and mass spectrometry methods needs to be altered with respect to the structure thereof as a substrate compound, such as the length of an alkyl chain contained therein, depending on...
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WO/2017/218888A1 |
Compositions and uses for steviol glycoside compounds having four glucopyranose residues attached via the number 13 carbon (C13) of the steviol moiety and a second group of two or three glucopyranose residues attached via the number 19 c...
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WO/2017/207754A1 |
The invention describes novel conjugates of formula (I) of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein allowing a reversible release of the pharmaceutical agent depending on the glucose concentration.
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WO/2017/202351A1 |
The present invention relates to a new crystal form of a sodium-glucose co-transporter inhibitor medicine (Sotagliflozin) and a preparation method and use thereof. In addition, the present invention relates to a pharmaceutical compositio...
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WO/2017/205269A1 |
Compounds of Formula (I), compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, haloalkyl ...
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WO/2017/199028A1 |
A method of preparing an active agent or a salt thereof from a prodrug first compound (1) comprising a propargyl group connected to an oxygen that is directly or indirectly connected to the active agent is provided, wherein the bond betw...
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WO/2017/196933A1 |
Methods of preparing freeze dried powders comprising rebaudioside M and rebaudioside D are provided herein. The freeze dried powders produced by the disclosed methods exhibit improved aqueous solubility over known forms and compositions ...
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WO/2017/185026A1 |
Reversibly blocked nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.
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WO/2017/184884A1 |
Provided are methods and yeast cultures for producing polyol lipids and polyol lipid compositions.
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WO/2017/177326A1 |
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to ta...
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WO/2017/178656A1 |
This invention generally relates to the field of phosphoramidite derivatives. In particular, the invention relates to N- Acetylgalactosamine (GalNAc) compounds, in particular phosphoramidite or phosphonoamidite molecules of formula (I) w...
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WO/2017/178497A1 |
The invention relates to a composition comprising one or more antimicrobial glycolipids and one or more formulation stabilizers. The invention also relates to methods of preparing the compositions and their application in water containin...
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WO/2017/179945A1 |
The present invention relates to an amphiphilic compound having a pentasaccharide hydrophilic group, a method for producing the same, and a method for extracting, solubilizing, stabilizing, crystallizing or analyzing a membrane protein a...
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WO/2017/174748A2 |
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine- leucinol dipeptide linked to the lipid oligomer...
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WO/2017/176999A1 |
Disclosed are oligonucleotides that binds specifically to HIV neutralizing monoclonal antibody 2G12 with a K4 value lower than 20 nM, the oligonucleotide comprising a predicted structure, at 37°C, having exactly one stem-loop whereby th...
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WO/2017/173019A1 |
This invention relates to novel compositions comprising the reaction product of at least one acetoacetylated polyol and vanillin. The invention also relates to a method of making the novel compositions of the invention comprising the rea...
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WO/2017/167652A1 |
The invention relates to a compound characterised by a chemical dexpanthenol bound to a saccharide. The invention also relates to a corresponding compound for use in therapeutic and/or cosmetic methods.
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