Heterocyclic Compounds

Matches 601 - 650 out of 2,235	< 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 >

Document	Document Title
WO/1996/039405A1	PYRIDINIMINYL-1,2-BENZISOXAZOLES AND- BENZISOTHIAZOLES AS ANTIPSYCHOTIC AGENTS Novel pyridiniminyl-1,2-benzisoxazoles and -benzisothiazoles, intermediates and processes for the preparation thereof, and methods of relieving memory dysfunction and treating depression utilizing the 1,2-benzisoxazoles and -benzisothiaz...
WO/1996/038144A1	ISOTHIAZOLONES Isothiazolones having general structure (I) where A is a monocyclic or bicyclic ring which may contain up to 3 heteroatoms selected from O, S, and N; R1 and R2 are substituent groups such as alkyl, alkoxy, hydroxy, nitro, cyano, amino, a...
WO/1996/036615A1	FUNGICIDAL CYCLIC AMIDES Cyclic amides of formula (I) which are useful as fungicides, wherein: A is O; S; N; NR5; or CR14; G is C or N; W is O or S; X is OR1, S(O)mR1 or halogen; R1, R2, and R5 are independently, in part, C1-C6 alkyl; Y is, in part, -O-; -S(O)n-...
WO/1996/035669A1	(HET)ARYLOXY-, -THIO-, AMINOCROTONATES, METHODS OF PREPARING THEM AND THEIR USE AS INSECTICIDES AND FUNGICIDES Described are (het)aryloxy-, -thio-, aminocrotonates of formula (I) in which the substituents are defined as follows: U is oxygen, sulphur or amino; V is oxygen, sulphur, amino or alkylamino; X, Y, Z, independently of each other, are =N-...
WO/1996/033167A1	PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES A process for preparing an aromatic or heteroaromatic sulfonyl halide of the general formula (3): Ar-(-SO2Y)n by halogenating an aromatic or heteroaromatic methyl sulfide of the general formula (1): Ar-(-SCH3-mXm)n or an aromatic or hete...
WO/1996/032940A1	NEW N-ACYLATED 4-HYDROXYPHENYLAMINE DERIVATIVES WITH ANALGESIC PROPERTIES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM The present invention relates to a series of new N-acylated 4-hydroxyphenylamine derivatives, linked via an alkylene bridge to the nitrogen atom of a 1,2-benzisothiazol-3(2H)-one 1,1-dioxide group, of formula (I), in which n is a number ...
WO/1996/029320A1	PROCESS FOR THE PREPARATION OF 1,2-BENZISOTHIAZOLIN-3-ONES A process for making a 2-alkylbenzisothiazolinone which comprises reacting a bisamide of formula (2) in water or an organic liquid containing water with a bisulphite or bisulphite release agent to form a Bunte salt and converting the Bun...
WO/1996/026929A1	4-AMINOTETRAHYDROBENZISOXAZOLE OR -ISOTHIAZOLE COMPOUNDS 4-aminotetrahydrobenzisoxazole or -isothiazole compounds having general formulae (Ia) and (Ib), wherein R1-R6, X and P are further defined in the description. The disclosed compounds have GABA (4-aminobutanoic acid) inhibiting activity a...
WO/1996/026200A1	HERBICIDAL BENZOYL DERIVATIVES The invention concerns benzoyl derivatives of formula (I) in which the substituents have the following meanings: L and M represent hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkinyl, C1-C4 alkoxy (these groups being optionally substitut...
WO/1996/026191A1	FUNGICIDAL CYCLIC AMIDES Compounds of formula I, and their N-oxides and agriculturally-suitable salts, are disclosed which are useful as fungicides (I) wherein A is O; S; N; NR5; or CR14. G is C or N; provided that when G is C, A is O, S or NR5 and the floating ...
WO/1996/026195A1	BENZOTHIAZINE DIOXIDES AS ENDOTHELIN ANTAGONISTS Novel benzothiazine dioxides which are antagonists of endothelin are described, as well as novel intermediates used in their preparation, methods for the preparation, and pharmaceutical compositions of the same, which are useful in treat...
WO/1996/026193A1	PHENYL DIKETONE DERIVATIVES Phenyldiketone derivatives have the formula (I), in which the substituents have the following meanings: L, M are hydrogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkinyl, C1-C4 alkoxy optionally substituted by 1 to 5 halogen atoms or C1-C4 al...
WO/1996/022978A1	SUBSTITUTED PHENYL COMPOUNDS AS ENDOTHELIN ANTAGONISTS Compounds of formula (I) are described, wherein: R1 is CN, CH2CN, CH=CHCN, CHO, or CH=CHCO2H; R2 is aryl lower alkoxy, heteroaryl lower alkoxy, aryl lower alkylthio or heteroaryl lower alkylthio in which each of the aryl and heteroaryl m...
WO/1996/022023A1	COMPOSITION AND USE The use of a 2-(C3-5-alkyl)-BIT or 2-aralkyl-BIT such as 2-phenylethyl-BIT as a fungicide for plastics materials. 2-n-butyl-BIT is preferred.
WO/1996/021435A1	COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram as well as with improved selectivity with regard to PDE III inhibition. In cert...
WO/1996/021656A1	ESTROGEN AGONISTS/ANTAGONISTS Compounds of formula (I) are useful for treating or preventing obesity, breast cancer, osteoporosis, endometriosis, cardiovascular disease and prostatic disease.
WO/1996/019465A1	NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION CONTAINING SAID NOVEL CLATHRATE COMPOUND A clathrate compound comprising a tetrakisphenol compound represented by general formula (I) as the host compound and a 2-alkyl-3(2H)-isothiazolone as the guest compound, wherein X represents (CH2)n; n represents 0, 1 or 2; and R1 to R8 ...
WO/1996/017834A1	PROCESSES FOR PRODUCING ISOTHIAZOLE DERIVATIVES A process for producing a 1,2-benzisothiazole by the reaction of a 2-(alkylthio)benzaldehyde oxime with a halogen compound; a process for producing a 3-halo-1,2-benzisothiazole by the reaction of a 1,2-benzisothiazole with a halogenating...
WO/1996/016954A1	DERIVATIVES OF ANTHRANILIC ACID USEFUL AS FUNGICIDES Compounds of formula (I), wherein A is a 5-membered optionally substituted, heteroaryl group comprising at least one hetero atom selected from nitrogen, sulfur and oxygen, which is optionally substituted by one or more of the group R2; R...
WO/1996/016034A1	PROCESS FOR PRODUCING AROMATIC OR HETEROAROMATIC SULFUR COMPOUNDS A process for producing an aromatic or heteroaromatic thiol represented by the following general formula (2): Ar-(-SH)n by hydrolyzing an aromatic or heteroaromatic halomethyl sulfide represented by the following general formula (1): Ar-...
WO/1996/011676A1	USE OF INHIBITORS OF CYCLOOXYGENASE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES The invention describes a method of treating neurodegenerative disorders such as Alzheimer's Disease by using a COX-2 inhibitor.
WO/1996/010012A1	NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS This invention relates to ortho substituted phenyl compounds as inhibitors of prostaglandin synthase, to pharmaceutical compositions comprising such compounds and to methods of using such compounds as antiinflammatory and antipyretic age...
WO/1996/005185A1	NOVEL ALKYLAMINO DERIVATIVES AS SIGMA 2 SELECTIVE LIGANDS The present invention relates to novel alkylamino derivatives of formula (I). These compounds exhibit a high selectivity and a high affinity for sigma 2 receptor and therefore are useful in the treatment of central nervous system disorde...
WO/1996/005184A1	HERBICIDAL SACCHARIN CARBOXYLIC ACID DERIVATIVES AND METHOD FOR THEIR PREPARATION The invention pertains to novel herbicidally effective saccharin carboxylic acids or carboxylic acid esters of formula (Ia), in which the substituents are as follows: L, M are hydrogen, C1-C4 alkyl, C1-C4 alkoxy C1-C4 alkylthio, chlorine...
WO/1996/005183A1	SACCHARINE DERIVATIVES AND THEIR USE AS HERBICIDES The invention concerns saccharine derivatives of the formula (I) in which the substituents are defined as follows: L, M hydrogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, chlorine, cyano, methylsulphonyl, nitro or trifluoromethyl; Z h...
WO/1996/005182A2	SACCHARIN DERIVATIVES Saccharin derivatives of formula (I) are disclosed, wherein the substituents have the following meanings: L, M stand for hydrogen, alkyl, alkoxy, alkylthio, chlorine, cyano, methylsulphonyl, nitro or trifluoromethyl; Z stands for hydroge...
WO/1996/005198A1	SACCHARINE DERIVATIVES The invention concerns saccharine derivatives of formula (I) in which the substituents are defined as follows: L, M hydrogen, C1-C4 alkyl, C1-C4 alkoxy, C1-C4 alkylthio, chlorine, cyano, methylsulphonyl, nitro or trifluoromethyl; Z hydro...
WO/1996/003380A1	AROMATIC AMINO ETHERS AS PAIN RELIEVING AGENTS The present invention relates to compounds of formula (I), wherein A is an optionally substituted phenyl, naphthyl, pyridyl, pyrazinyl, pyridazinyl, pyrimidyl, thienyl, thiazolyl, oxazolyl, thiadiazolyl having at least two adjacent ring ...
WO/1996/002525A1	NOVEL ARYL PIPERAZINE-DERIVED PIPERAZIDE DERIVATIVES, METHODS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME Novel 5HT receptor antagonists of general formula (I) in which Ar1 and Ar2 are an aromatic residue, X is O, NH, CH2O or CH2NH, R1 is hydrogen, a linear or branched alkyl chain comprising 1-6 carbon atoms. The invention also concerns the ...
WO/1996/000720A1	ARYL AND HETEROARYL ALKOXYNAPHTHALENE DERIVATIVES Compounds of formula (I) wherein R1, R2, R4, R23, R24, R25 and R26 are defined as in the specification. These compounds are useful psychotherapeutics and are potent serotonin (5-HT1) agonists and antagonists.
WO/1996/000218A1	COMPOUNDS FOR AND METHOD OF INHIBITING PHOSPHODIESTERASE IV Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess similar or improved PDE IV inhibition as compared to rolipram, with improved selectivity with regard to, e.g., PDE III inhibition. Preferred compo...
WO/1995/033746A1	CYCLIC SULFONAMIDE HERBICIDES Compounds of formula (I) and (II), and their agriculturally-suitable salts, are disclosed which are useful for controlling undesired vegetation, wherein X is a direct bond, O, S, NH, N(C1-C3 alkyl), N(C1-C3 haloalkyl) or N(allyl); R1 is ...
WO/1995/031448A1	N-(5-ISOTHIAZOLYL)AMIDE PESTICIDES This invention relates to novel N-(5-isothiazolyl)amide compounds of formula (1, 2, or 3), and compositions useful as nematicides, insecticides, miticides, and plant fungicides. The present invention also provides nematicidal, insecticid...
WO/1995/030651A1	N-SULPHONYL AND N-SULPHINYL AMINO ACID AMIDES AS MICROBIOCIDES 'alpha'-amino acid amides of formula (I), in which n is the number zero or one; R1 is C1-C12alkyl, which is unsubstituted or can be substituted by C1-C4alkoxy, C1-C4alkylthio, C1-C4alkylsulfonyl, C3-C8cycloalkyl, cyano, C1-C6alkoxycarbon...
WO/1995/026959A1	ALKYLENEDIAMINE DERIVATIVE A novel alkylenediamine derivative having the effect of inhibiting dysuria occuring under a high intravesical pressure and represented by general formula (1) wherein R1 represents hydrogen, alkyl, halogen, haloalkyl, hydroxy, alkoxy, nit...
WO/1995/025727A1	NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS Naphthylamides are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as antipsychotic agents and as agents for the trea...
WO/1995/024403A1	(4,4-DIFLUOROBUT-3-ENYLTHIO)-SUBSTITUTED HETEROCYCLIC OR CARBOCYCLIC RING COMPOUNDS HAVING PESTICIDAL ACTIVITY A compound of formula (I), or a salt thereof, wherein n is 0, 1 or 2; and R is a group of formulae (II) to (XXI), wherein: the S(O)nCH2CH2CH=CF2 group is at least one of R1 (when attached to a carbon atom), R2, R3, R4, R5 or R6; R1 (when...
WO/1995/021153A1	PHENYL ACETIC ACID DERIVATIVES, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND AGENTS CONTAINING THEM Phenyl acetic acid derivatives of formula (I) in which the components and index have the following meanings: X is NOCH3, CHOCH3 CHCH3 and CHCH2CH3; R1 is hydrogen and alkyl; R2 is cyano, nitro, trifluoro methyl, halogen, alkyl and alkoxy...
WO/1995/020578A1	SUBSTITUTED AROMATIC COMPOUNDS AS c.AMP PHOSPHODIESTERASE- AND TNF-INHIBITORS This invention is directed to compounds of formula (I), wherein R1 is an optionally substituted lower alkyl group; R2 is an optionally substituted oxaaliphatic group; R3 is an optionally substituted aryl group or an optionally substitute...
WO/1995/020014A1	MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF A process for colouring a synthetic textile material or fibre blend thereof which comprises applying to the synthetic textile material a compound or mixture thereof, which is free from water solubilising groups, of the Formula (1) A-N=N-...
WO/1995/018799A1	PHENYL HETEROCYCLES AS COX-2 INHIBITORS The invention encompasses the novel compound of Formula (I) useful in the treatment of cyclooxygenase-2 mediated diseases. The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated dise...
WO/1995/018797A1	NOVEL SERINE PROTEASE INHIBITORS: DERIVATIVES OF ISOTHIAZOLIDIN-3-ONE-1,1 DIOXIDE AND 3-OXO-1,2,5-THIADIAZOLIDINE-1,1-DIOXIDE Isothiazolidin-3-one-1,1 dioxide, 3-oxo-1,2,5-thiadiazolidine-1,1-dioxide and derivatives thereof, reduce or inhibit the activity of serine proteases. Such compounds are useful as anti-inflammatory and anti-metastatic agents.
WO/1995/018111A1	COMPOUNDS CONTAINING BASIC AND ACIDIC TERMINI USEFUL AS FIBRINOGEN RECEPTOR ANTAGONISTS This invention relates to novel compounds containing basic and acidic termini, pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combinatio...
WO/1995/015309A1	DP-IV-SERINE PROTEASE INHIBITORS Compounds selected from those of general formula [A-B (Groups I and II)] and (group III), (1, 2 and 3) where B is (4) and A is selected from specified aminoacyl compounds are inhibitors of DP-IV mediated processes.
WO/1995/014009A1	FUNGICIDAL CYCLIC AMIDES Cyclic amides of Formula (I) which are useful as fungicides wherein: A is O; S; N; NR5; or CR14; G is C or N; W is O or S; X is OR1, S(O)mR1 or halogen; R1, R2, and R5 are independently, in part, C1-C6 alkyl; Y is, in part, -O-; -S(O)n-;...
WO/1995/013262A1	SUBSTITUTED PHENYL COMPOUNDS Compounds of formula (I) are described wherein R1 is hydrogen, -(lower alkyl)q(CO2R6 or OH), -CN, -C(R7)=NOR8, NO2, -O(lower alkyl)R9, -CC-R10, -CR11=C(R12)(R13), -C(=O)CH2C(=O)CO2H, -CO(R14), alkylthio, alkylsulphinyl, alkylsulphonyl, c...
WO/1995/012587A1	5-ARYLISOXAZOL-4-YL-SUBSTITUTED 2-AMINO CARBOXYLIC ACID COMPOUNDS 2-Aminocarboxylic acid compounds substituted with 5-arylisoxazol-4-yl or 5-arylisothiazol-4-yl and having general formula (I), wherein A is a bond or a spacer group; B is a group -CH(NR'R'')-COOH wherein R' and R'' are independently hydr...
WO/1995/011680A1	HETEROARYLPIPERIDINES, PYRROLIDINES AND PIPERAZINES AND THEIR USE AS ANTIPSYCHOTICS AND ANALGETICS Heteroarylpiperidines, pyrrolidines, and piperazines are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses-treating effective amount of one o...
WO/1995/011278A1	DIPHENYLAMINE COMPOUNDS Diphenylamines have formula (I), in which the ring A may be benzoanellated; D stands for an aryl radical or for a five-membered aromatic heterocyclic residue that has 1 to 3 heteroatoms in the heterocyclic ring selected from the group th...
WO/1995/010507A1	PHENYLSULFONYL UREAS, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS Compounds are disclosed having the formula (I), as well as their salts, as they are defined in the first claim. In the formula (I), R1 stands for CO-Q-R8, in which R8 = H or R; R2, R3 stand for H or (C1-C4)alkyl; R4 stands for H, R, RO, ...

Matches 601 - 650 out of 2,235	< 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 >