| Document |
Document Title |
|
WO/2009/136365A1 |
The present invention relates to a process for the preparation of threo-3,4-epoxy-2- amino-1-substituted butane derivatives represented by general Formula I which comprises reacting compound of Formula III or salt thereof with an active ...
|
|
WO/2009/118341A1 |
The invention relates to a method for producing aldehydes by reacting an α,β-unsaturated carboxylic acid or the salt thereof with carbon monoxide and hydrogen in the presence of a catalyst, said catalyst comprising at least one complex...
|
|
WO/2009/115538A1 |
The object of the invention is a method for producing urethanes through reaction of aromatic amines with a dialkyl carbonate, characterized in that the alkyl radical of the organic dialkyl carbonate has 2-18 carbon atoms and the reaction...
|
|
WO/2009/115537A1 |
The invention provides metal carbamates of the general formula (I) where R1 and R2 are each an alkyl group.
|
|
WO/2009/113608A1 |
Provided is a process by which a urethane (meth)acrylate can be safely produced with satisfactory productivity. The process is a continuous process for urethane (meth)acrylate production which comprises causing a liquid mixture of a comp...
|
|
WO/2009/108484A1 |
The present invention provides novel synthesis's for obtaining a protecting group aminoxy PEG-6 linker from cost effective, and readily available starting materials and chemicals or modified polyethylene glycols. More specifically, a nov...
|
|
WO/2009/098327A1 |
Method for producing fluorinated carbamates that comprises the reaction between an amine or polyamine and a fluorinated carbonate in the presence of a catalyst in the presence of basic heterogeneous catalysts. The method may also compris...
|
|
WO/2009/096545A1 |
A diurethane compound R2(SO2)m(CH2)nOCONH-R1-NHCOO(CH2)n(SO2)mR2 is produced by a method in which a diamine compound H2NR1NH2 is reacted with a chloroformate compound ClCOO(CH2)n(SO2)mR2 or by a method in which a diisocyanate compound OC...
|
|
WO/2009/095164A1 |
The invention relates to a method for producing urethanes by the oxidative carbonylation of amino compounds in the presence of carbon monoxide, oxygen and organic compounds carrying hydroxyl groups, characterized in that the carbonylatio...
|
|
WO/2009/094563A2 |
A crystalline form of Ca-salts of (3S) -aminomethyl-5-hexanoic acids and methods of preparing a crystalline form of a (3S) -aminomethyl-5-hexanoic acid and methods of using a crystalline form of a (3S) -aminomethyl-5-hexanoic acid are pr...
|
|
WO/2009/094569A2 |
Methods of enzymatically resolving acyloxyalkyl thiocarbonates useful in the synthesis of acyloxyalkyl carbamates are disclosed. These carbamates can be coupled to drugs containing amines such as R-baclofen or S-pregabalin.
|
|
WO/2009/090251A2 |
The invention relates to a process for producing NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone. In detail, the new processes, according ...
|
|
WO/2009/078396A1 |
The object is to provide a method for improving the yield in the radioactive fluorination in the process for producing a radioactive-fluorine-labeled organic compound. Provided is a method for labeling a compound represented by the formu...
|
|
WO/2009/075291A1 |
Disclosed is a novel optically active dinickel complex. Also disclosed is a method for producing a novel optically active amine by an asymmetric Mannich reaction using the optically active dinickel complex as a catalyst. Specifically dis...
|
|
WO/2009/054240A1 |
Hexamethylphosphoramide (HMPA) is added to a reaction vessel containing (R)-1,1'-binaphthyl-2,2'-dithiol and potassium hydroxide. The reaction vessel is purged with oxygen, and is stirred at 80°C for 5 days under 7 atmospheres of oxygen...
|
|
WO/2009/050587A1 |
The present invention relates to a process of preparing a compound of Formula I: (I) Formula I Wherein R1 is defined in the specification. Compounds of Formula I are useful for treating disorders of the central nervous system, including ...
|
|
WO/2009/044707A1 |
Disclosed is a nitrotriazole derivative represented by the general formula (I) below. This nitrotriazole derivative is a compound useful as a synthesis reagent for synthesizing a carbamate, a carbonate and a thiocarbonate, which are usef...
|
|
WO/2009/018939A1 |
The present invention relates to a process for heterogeneously catalyzed partial esterification of (meth)acrylic acid with oxyalkylated polyols, wherein the oxyalkylated polyols have at least 3 free hydroxyl groups, and wherein the catal...
|
|
WO/2009/016879A1 |
It is intended to provide a process for producing an optically active N-(halopropyl)amino acid derivative. This method comprises: the step wherein an optically active alanine ester represented by the formula (I) or its salt (hereinafter ...
|
|
WO/2009/013062A1 |
Process for the synthesis of non cyclic carbamate derivatives from amine compounds, alcohols and CO2 in the presence of ionic liquids and optionally in the presence of a base.
|
|
WO/2008/151992A2 |
The present invention provides a novel method for preparing a key intermediate, 3-amino-pentan-l,5-diol (2), which is useful for the preparation of 6-(2,4- difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino
]-8-methyl-8H- pyrid...
|
|
WO/2008/151785A1 |
The invention relates to a method for producing a compound which has at least one ether group, at least one ester group, at least one amino group or at least one urethane group, preferably at least one ester group. The method according t...
|
|
WO/2008/151784A1 |
The invention relates to a method for producing 1,2 propandiol by hydrogenation of glycerol using hydrogen gas, wherein glycerol is reacted with hydrogen to give 1,2 propandiol. This reaction is carried out in at least i reactors R1 to R...
|
|
WO/2008/142100A1 |
The invention relates to an improved method for producing carbonate-terminated urethanes using isocyanates. The method according to the invention is characterized by high yields with no phenol being produced as a secondary component.
|
|
WO/2008/139467A2 |
The present disclosure provides processes for the preparation of lipid conjugated cyclic carbonate derivatives. More specifically, the present disclosure is based on the finding that reacting lipids, such as, ceramides, with N,N'-disucci...
|
|
WO/2008/135273A1 |
Urethane and oligourethane derivatives and corresponding uses and methods of producing watermarks using the offset printing technique. The invention relates to compounds having general formula (R-O-CO-NH-X-NH-CO-O-(-A-O-CO-NH-X'-NH-CO-O-...
|
|
WO/2008/134326A1 |
This invention is a composition comprising a regioisomeric branched aldehyde (2) where Boc is -C(O)OC(CH3)3 and optionally an additional aldehyde of formula (1). The invention is also a method of making the compositions.
|
|
WO/2008/124969A1 |
The present invention provides a preparation method of rivastigmine and its intermediates. The present invention provides a preparation method of the formula (1) compound by reacting the formula (2) compound with CH3X or CH3CH2X in the p...
|
|
WO/2008/125486A1 |
The invention relates to a process for the preparation of N-protected α-aminoaldehydes by deacetalization of the acetal functional group of corresponding N-protected α-aminoacetals using formic acid.
|
|
WO/2008/120475A1 |
Disclosed is a method for producing an alcohol from a lactone or a carboxylic acid ester, which enables to produce an alcohol from a lactone or a carboxylic acid ester under relatively mild conditions with high yield and high catalytic e...
|
|
WO/2008/120567A1 |
Disclosed is a method for collecting an L-biphenylalanine compound salt (2'), which comprises the steps of: hydrolyzing a biphenylalanine ester compound (1) with a protease derived from a microorganism belonging to the genus Bacillus in ...
|
|
WO/2008/102680A1 |
Disclosed is a hyperbranched polymer having a main chain of polyamide structure and a terminal amino group, which does not require a large amount of an organic solvent during production. This hyperbranched polymer has high transparency a...
|
|
WO/2008/083967A2 |
The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, p...
|
|
WO/2008/084086A1 |
The present invention relates to a method for the production of o-vinylcarbamates or vinylcarbonates, wherein a secondary amine or an alcohol is reacted with an alkyne compound in the presence of a catalyst selected from among carbonyl c...
|
|
WO/2008/077672A1 |
The invention relates to a multi-stage process for the continuous, phosgene-free preparation of (cyclo)aliphatic diisocyanates that comprises the conversion of (cyclo)aliphatic diamines into the corresponding (cyclo)alkylene biscarbamate...
|
|
WO/2008/059051A1 |
The invention relates to a process for the production of an imide (1) (2) (3) via the enantioselective addition of an amine (2) to an alkene (3) wherein Y is OR, wherein R is alkyl or Bn, said process comprising: incubating Pd(OTf)2 with...
|
|
WO/2008/049972A1 |
The present invention relates to carbamoylation of amines, mercaptanes, thiophenols and phenols employing organic azides. More specifically, the invention relates to a method for generating urea derivatives, thiocarbamate derivatives and...
|
|
WO/2008/046889A1 |
The invention relates to an insect- and mite-repelling agent, characterized by a content of at least one substituted, enantiomer-enriched α-,ω-amino alcohol derivative of formula (1) wherein X represents hydrogen, COR11 or R13, R13 rep...
|
|
WO/2008/043798A1 |
A process for the preparation of for the preparation of β-amino aldehydes and derivatives thereof, in particular β-amino acids and Υ-amino alcohols, by reacting carbamate-protected imines and unmodified aldehydes in the presence of an...
|
|
WO/2008/037433A1 |
The invention relates to a process for making the compound of general formula (I), or an acid addition salt wherein the dotted line indicates a carbon-carbon bond on the asymmetric carbon, which process comprises the steps of a) the reac...
|
|
WO/2008/037503A2 |
The invention relates to a process for making the compound of general formula (I), or an acid addition salt wherein the dotted line indicates a carbon-carbon bond on the asymmetric carbon, which process comprises the steps of a) the reac...
|
|
WO/2008/026678A1 |
Disclosed is a process for producing an optically active succinic acid imide derivative (3) which is a key intermediate for the production of ranirestat. The derivative (3) can be produced readily by treating a succinic acid diester deri...
|
|
WO/2008/022976A1 |
Pharmacological inhibition of fatty acid amide hydrolase (FAAH) activity leads to increased levels of fatty acid amides. The alkylcarbamic acid aryl ester of Formula (I), KDS-4103, is a FAAH inhibitor. Described herein is a process for t...
|
|
WO/2008/020452A1 |
The present invention relates to an improved process for preparation of Rivastigmine of formula (I) or pharmaceutically acceptable salts thereof comprising a step of N-methylation of compound of formula (III), wherein R1 = R2 = H or R1 =...
|
|
WO/2008/014811A1 |
A process for the preparation of ω-alkoxycarbonylamino-α-aminoacids and α,ω orthogonally diprotected diaminoacids from α,ω-diaminoacids using 1- alkoxycarbonylbenzotriazoles as protecting agents is disclosed. In an alternative embo...
|
|
WO/2008/013269A1 |
Disclosed is an isoquinuclidine derivative which enables to easily synthesize oseltamivir or an analogue thereof. Specifically disclosed is an isoquinuclidine derivative represented by the formula (1) below or a mirror image structure of...
|
|
WO/2008/007670A1 |
A process for the production of a compound having a primary, secondary or tertiary aminomethyl-aromatic ring, characterized in that a fluoroboron compound represented by the formula (I): Ra(Rb)N-CH2-BF3M (I) or a dimmer thereof or a solv...
|
|
WO/2007/136323A1 |
The present invention relates to a process for the production of a compound of formula (I) comprising a reduction of the carboxyl and cyanide groups of a compound of formula (III), followed by resolvation of the racemic product into the ...
|
|
WO/2007/132277A1 |
The compounds of the general Formula (I), wherein R1 is aryl or alkyl; R2 represents alkyl; R3 represents alkyl or aralkyl, are valuable pharmaceutical intermediates, which can be prepared by reacting a compound of the general Formula (I...
|
|
WO/2007/111024A1 |
An ethylenediamine derivative having a halogenated carbamate group and an acyl group can be produced by performing the catalytic hydrogenation of an aminonitrile having a halogen-substituted carbamate group in the presence of an acid and...
|
