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WO/2013/131484A1 |
The present invention provides novel processes for the preparation of N-substituted benzamides having the formula (VIc). In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically acti...
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WO/2013/125324A1 |
The present invention addresses the problem of providing a process for preparing an oxime in a high yield by ammoximating a ketone with both an organic peroxide and ammonia. This process is characterized by ammoximating a ketone with an ...
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WO/2013/119751A1 |
The present invention relates to a process of making a compound of formula (I), wherein, R1, R2, R4 and X are as defined herein.
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WO/2013/105342A1 |
The present invention relates to an evaporator that includes: a plurality of heating tubes; an upper tube plate that supports the plurality of heating tubes with spaces therebetween; and a first dispersion plate provided above the upper ...
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WO/2013/057743A1 |
The invention relates to a process for the preparation of 3-cyano-3-{4-[(4-{[(2Z)-2-(methoxyimino)-2-phenylethyl] oxy} benzyl) oxy] phenyl} propanoic acid or salts thereof. In one form, the invention relates to the process for the prepar...
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WO/2013/046781A1 |
The invention pertains to a compound shown by the formula (I) and a process for the manufacture thereof. (In the formula, Ax represents an organic group having 2-30 carbon atoms having at least one aromatic ring of an aromatic hydrocarbo...
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WO/2013/011518A1 |
The invention relates to process for the preparation of 2-amino-4-(4- fluorobenzylamino)-l-ethoxycarbonylaminobenzene generically known as Retigabine of the formula (I) and its pharmaceutically acceptable salts e.g. Formula IA, particula...
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WO/2013/007054A1 |
The present invention relates a method for preparation of ketoxime compound, comprising: feeding a ketone compound, hydrogen peroxide, water, and ammonia into a reactor for contact reaction under the conditions of oximation reaction of k...
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WO/2012/155764A1 |
An α-diimine metal complex catalyst, wherein the metal may be nickel or palladium. The catalyst may be used for direct catalytic polymerization of olefins to provide the olefin polymer, further preparing the highly branched alkane mixtu...
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WO/2012/152600A1 |
Ammoximation reactor for cyclohexanone oxime production comprising: (a) a reactor vessel provided with a stirrer; (b) an internal filtering system; (c) an internal liquid ammonia evaporation coil; (d) an internal gaseous ammonia toroidal...
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WO/2012/147904A1 |
The present invention relates to a polymerizable compound indicated by formula (I). The present invention provides a polymerizable compound, a polymerizable composition, a polymer, and an optically anisotropic material that are capable o...
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WO/2012/122854A1 |
Disclosed in the present invention are an asymmetric (α-diimine) nickel complex catalyst and preparation method and use thereof. The complex is as shown in formula I, wherein Rl is a diphenylmethyl, R2 is methyl or diphenylmethyl, R3 is...
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WO/2012/108367A1 |
A quaternary ammonium salt shown by formula (5) (in the formula, R1 represents a C1-4 alkyl group; R2 represents a C1-10 alkyl group; R3 represents a C1-10 alkyl group optionally substituted with one or more phenyl groups or a phenyl gro...
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WO/2012/083953A1 |
The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is -NR11R12; and pharmaceutic...
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WO/2012/074168A1 |
The present invention relates to a method for preparing MHB (methyl-4-hydroxyiminobenzoate) from by-products generated in a process for preparing DMT (dimethyl terephthalate). The method comprises: (a) adding alcohol to reaction by-produ...
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WO/2012/066134A1 |
A process for preparing azomethines of the general formula (V) where R is an optionally substituted carbocyclic aromatic radical having 6 to 24 carbon atoms or an optionally substituted alkyl radical or an optionally substituted heteroar...
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WO/2012/059436A2 |
The invention relates to novel compounds of formula (I), in which R1, R2, R3, R4, R5, Y, Q and G are defined as indicated above, to several methods and intermediate products for the production thereof and use thereof as herbicides and/or...
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WO/2012/059441A2 |
The present invention relates to a method for preparing 4-chloro-, 4-bromo- or 4- iodobenzaldehyde oximes and phenyl-substituted isoxazoline compounds prepared from these oximes.
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WO/2012/057709A1 |
Compounds of formula (I): wherein R1 to R8, and X- are defined herein. Also disclosed are methods of making and using these compounds.
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WO/2012/003708A1 |
A composite catalyst of Ti-Si molecular sieve and resin, preparation method and application thereof are disclosed. The catalyst is mainly consisted of Ti-Si molecular sieve and resin. The preparation method is as follows: mixing Ti-Si mo...
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WO/2012/000421A1 |
Disclosed are gossypol derivatives, preparation methods and uses thereof in the manufacture of antitumor medicaments. Pharmaceutical compositions containing the said gossypol derivatives and preparation methods thereof are also disclosed.
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WO/2011/152476A1 |
Disclosed are: a condensed polycyclic aromatic compound which has excellent responsiveness to a lithium ion and is suitable for use in a lithium ion secondary battery; a process for producing the condensed polycyclic aromatic compound; a...
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WO/2011/118647A1 |
Disclosed is a method for producing an oxime characterized by reacting a ketone and hydroxylamine in the presence of carboxylic acid and/or a salt thereof in a system formed from an aqueous phase and a hydrophobic solvent phase.
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WO/2011/108512A1 |
Provided is a novel azomethine oligomer which can ensure sufficient carrier mobility for use as a semiconductor material and which can dissolve in relatively versatile organic solvents, for example, hydrophobic solvents such as toluene, ...
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WO/2011/105632A1 |
A process for producing a hydroxyiminoalkenyl cyclopropanecarboxylic acid ester represented by formula (3) (wherein R1 represents an alkyl group which may have a substituent, or a halogen atom; and R2 represents an alkyl group which may ...
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WO/2011/095563A1 |
The present invention pertains to a process for preparing an oxime in which a carbonyl compound is reacted in the liquid phase with NH3 and H2O2 in the presence of a catalyst to form the corresponding oxime, characterised in that the cat...
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WO/2011/093423A1 |
Disclosed is a method for producing a compound represented by formula (E)-I characterized by comprising precipitating crystals of the compound represented by formula (E)-I in the coexistence of an acid and shifting the equilibrium of the...
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WO/2011/093394A1 |
Provided is a novel compound which ensures sufficient carrier mobility for use as a semiconductor material and which can dissolve in relatively general-purpose organic solvents such as hydrophobic solvents (such as toluene), alcoholic so...
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WO/2011/010677A1 |
Provided is a process for economically producing from 2-hydroxybutyronitrile a 2-aminobutylamide inorganic acid salt which is useful as a starting material for medicines, etc. 2-Hydroxybutyronitrile is reacted with ammonia to obtain a li...
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WO/2011/007877A1 |
Disclosed are: a method for producing an optically active epoxy compound; a ligand which is used in the method; a complex; a method for producing the ligand; and a method for producing the complex. Specifically disclosed are: a complex w...
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WO/2010/142841A1 |
The invention relates to a method and apparatus for restoring the extractive potential of organic hydroxyoxime-based extraction solution used in the recovery of metals by liquid-liquid extraction. The method is two-stage, in which an aqu...
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WO/2010/139520A1 |
According to the present invention, a method for separating a primary amine being an N,N- dialkylbisaminoalkylether, from mixtures comprising said primary amine and at least one of a secondary amine being an N,N,N'-trialkylbisaminoalkyle...
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WO/2010/097350A1 |
The invention relates to a process for the preparation of an aldehyde beta-lactam compound of formula (I), wherein P1 is H or a protecting group, useful in the preparation of ezetimibe, from a nitrone compound of formula (II). The nitron...
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WO/2010/089267A2 |
The present invention relates to a process for producing 2-halogenomethylphenyl acetic acid derivatives.
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WO/2010/091069A1 |
[0070] A gasoline deposit control additive composition for use in a fuel comprising from about 70 to about 95 volume percent of hydrocarbons in the gasoline boiling range and from about 5 to about 30 volume percent of at least one alcoho...
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WO/2010/084459A2 |
The present invention provides an improved process for preparation of N-[4-(3,4- dichlorophenyl)-3,4-dihydro-1-(2H)-naphthalenylidene]methana
mine (ketimine) comprising condensation of 4-(3,4-dichlorophenyl)-3,4-dihydro-1-(2H)-naphthalen...
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WO/2010/079324A1 |
A redox ammoximation process in which a ketone or aldehyde is reacted with ammonia and oxygen in the presence of a catalyst, wherein: the catalyst is an aluminophosphate based redox catalyst having the qualitative general formula (I) M1M...
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WO/2010/069266A1 |
The heterocyclic nitrogenous or oxygenous compounds of formula (A), (B), (C) or (D) formed from dialdehydes, their optical isomers, cis- and trans- isomers, or agrochemically acceptable salts, their preparation methods, agrochemical comp...
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WO/2010/060277A1 |
Substituted acetyl hydrazide derivatives of formula (I) and compounds of formulas a-c with the action of inhibiting tumor cells, their pharmaceutical salts or solvates, their preparation, their pharmaceutical composition comprising the c...
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WO/2010/059913A2 |
The present invention relates to processes for the preparation of rasagiline mesylate. Also provided is rasagiline mesylate having 90 volume percent of the particles (D90) with sizes less than about 6 μm and processes for the preparatio...
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WO/2010/055255A1 |
Method for preparing eplivanserin hemifumarate.
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WO/2010/043738A1 |
The present invention relates to a procedure for the selective hydrogenation of nitrocycloalkanes, substituted or not, comprising carrying out a catalytic hydrogenation of said compounds utilising a catalyst comprising at least one metal...
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WO/2010/040774A2 |
The invention relates to a process for converting ammonium formed in a hydroxylamine phosphate oxime process into molecular nitrogen in an ammonium destruction zone, comprising - preparing a vapour stream comprising nitrogen oxide from a...
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WO/2010/026031A1 |
The invention relates to a system for carrying out chemical reactions, comprising a reactor (1), the reaction chamber of which contains hydrogen peroxide (H2O2) and titanium silicalite (TS-1) (Figure 3). The object of the invention is to...
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WO/2009/137810A2 |
Methods are provided for the catalytic hydroamination of compounds having an alkyne or allene functional group, in which the compound is contacted with ammonia or an amine in the presence of a catalytic amount of a gold complex under con...
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WO/2009/116320A1 |
Disclosed is a process for producing a protected optically active fluoroamine, which comprises the step of reacting an imine-protected optically active hydroxyamine, an oxazolidine-protected optically active hydroxyamine, or a mixture of...
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WO/2009/113409A1 |
Provided is an efficient technology for synthesizing diamino acids (diamino acid derivatives). Disclosed is a manufacturing method for diamino acid derivatives wherein the fluorenyl groups of the diamino acid derivative starting material...
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WO/2009/094867A1 |
The present invention relates to a the heterocyclic or splitring nitrogenous compounds of formula (A), where R1-R5, Y, Z and W are as defined in the specification. The present invention discloses the preparation and the uses of an insect...
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WO/2009/090320A1 |
The invention relates to a method for preparing a compound of formula (I), wherein P1 and P2 are groups protecting the carboxylic acid and oxyamine functions, starting from pyroglutamic acid (S). The invention also relates to novel inter...
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WO/2009/054202A1 |
A method of organic-compound reaction and a process for producing an organic compound. By the method and process, high reaction selectivity and a high yield of a target substance can be ensured according to purposes. At least two fluids ...
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