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WO/2016/116607A1 |
The present invention relates to an improved process for the racemization of (S) -1-aminoindane. (S) -1-aminoindane is formed as a side product in the process of preparation (R) -1-aminoindane by enantiomeric resolution of racemic 1-amin...
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WO/2016/113757A1 |
The present invention provides a novel recyclable catalysts of formula A, [Formula A should be inserted here] wherein X is selected from the group consisting of [Formula should be inserted here] The present invention also provides a nove...
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WO/2016/108941A1 |
The present disclosure provides a method for reducing the aldehyde content in an amine catalyst by treating the amine catalyst with a treating agent selected from a non-cyclic amide substituted with an isocyanate reactive group, a guanid...
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WO/2016/108712A1 |
The invention relates to the field of organic synthesis, and more particularly to a method of producing N,N-disubstituted aminomethylstyrenes or α-aminomethylstyrenes of general formula (I), which includes reacting a secondary amine of ...
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WO/2016/096905A1 |
This invention concerns the first mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalystand amine donor. The initial heterogeneous metal- catalyzed reaction between the ca...
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WO/2016/095870A1 |
Provided are a bisphenol and diamine containing benzocyclobutene structural unit, and preparation and application thereof; specifically, the present invention uses 4-halo-benzocyclobutene as a raw material to obtain 4-acyl-benzocyclobute...
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WO/2016/095136A1 |
Provided is a method for purifying 1,5-pentanediamine comprising: providing 1,5-pentanediamine to be purified and treating the 1,5-pentanediamine to be purified by a reduction reaction to obtain purified 1,5-pentanediamine. Meanwhile, fu...
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WO/2016/097914A1 |
The present invention discloses a process for preparation of white curcumin from purified curcuminoids. The curcuminoids are obtained by solvent extraction and crystallization of dried turmeric powder. The autoclave is charged with ethyl...
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WO/2016/093193A1 |
This method for manufacturing an N,N,N-trimethyl adamantyl ammonium hydroxide has, in sequence, (A) a step for obtaining an N,N-dimethyl adamantyl amine by dimethylating 1-aminoadamantane, (B) a step for reacting the N,N-dimethyl adamant...
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WO/2016/083210A1 |
The invention relates to a method for producing trans-enriched MDACH, characterized in that an MDACH starting mixture is distilled in the presence of an auxiliary agent. Trans-enriched MDACH is distilled, and - the auxiliary agent is an ...
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WO/2016/084565A1 |
Provided is a method for manufacturing a compound having an excellent reaction rate (high reaction rate). The method for manufacturing a compound includes a step for supplying, into a reaction vessel: compound (1) which has at least one ...
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WO/2016/080551A1 |
A catalyst fibrous structure having a catalyst metal carried on a fibrous structure, wherein (a) a Log differential micropore volume distribution curve thereof obtained by measurement using a mercury intrusion technique has a peak having...
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WO/2016/074121A1 |
Providing a process for forming an amine, such as a primary, a secondary or a tertiary amine, via the direct amination of an alcohol using a catalyst comprising at least a palladium compound on a support comprising cerium oxide.
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WO/2016/071249A1 |
The present invention relates to a novel method for producing substituted biphenylamines.
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WO/2016/071410A1 |
Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, wherein the halogen ato...
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WO/2016/071849A1 |
The present invention relates to a process for preparing Lomitapide or its pharmaceutically acceptable salt thereof having high purity with acceptable levels of impurities.
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WO/2016/066835A1 |
The present invention relates to a mild method of reducing a C-O bond to the corresponding C-H bond in a substrate, which could be a benzylic alcohol, allylic alcohol, ester or an ether bond beta to a hydroxyl group or alpha to a carbony...
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WO/2016/063300A1 |
The present invention provides a process for the preparation of compound of Formula I; wherein X is selected from the group consisting of fluorine, chlorine, bromine and iodine; Y is selected from X and -NR1R2; R1 and R1, independent of ...
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WO/2016/058504A1 |
An aromatic amine derivative as shown in the general formula I and a synthesis method and use thereof and an organic electroluminescent device. The compound has a symmetrical structure, is easy to synthesize, has a relatively high molecu...
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WO/2016/058207A1 |
Provided is a preparation method for 3-aminomethyl-3,5,5-trimethyl cyclohexylamine. The method comprises: a) controlling the acid number of 3-cyano-3,5,5-trimethyl cyclohexanone at 0.02 - 0.50 mg KOH/g, reacting with liquid ammonia to ob...
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WO/2016/057770A1 |
The present disclosure describes a method of coupling a first compound to a second compound, the method comprising: providing the first compound having a fluorosulfonate substituent; providing the second compound comprising an amine; and...
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WO/2016/042260A1 |
The invention relates to a method for reducing nitrated aromatic compounds into the corresponding aromatic amine under subcritical conditions.
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WO/2016/040661A1 |
Disclosed is method and apparatus for at least partially hydrogenating an organonitrile by reducing an iron oxide catalyst precursor contained in a movable cartridge comprising a casing, an inlet standpipe and at least one exit aperture,...
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WO/2016/039479A1 |
Provided is a catalyst which is able to be easily produced at low cost and has high activity and a long service life, while being suppressed in leakage of a metal. Some embodiments of the present invention provide a catalyst which is cha...
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WO/2016/040783A1 |
Tertiary amine catalysts having isocyanate reactive groups capable of forming thermally stable covalent bonds able to withstand temperatures from 120oC and higher and up to 250oC are disclosed. These catalyst can be used to produce polyu...
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WO/2016/035081A1 |
The present invention provides a system and method of storing hydrogen (H2) and releasing it on demand, comprising and making use of diaminoalkanes and alcohols, or aminoalcohols as liquid-organic hydrogen carrier systems (LOHC). 2-amino...
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WO/2016/035080A1 |
The present invention relates to novel Ruthenium complexes of formulae A1-A4 and their use, inter alia, for (1) dehydrogenative coupling of alcohols to esters; (2) hydrogenation of esters to alcohols (including hydrogenation of cyclic es...
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WO/2016/033115A1 |
In one embodiment, the invention presents a process for the preparation of N-alkyl polyamines that includes (i) the conversion of an amino alcohol to an aminoalkyl alkylating agent with a halo or aldehyde reactive group and (ii) the addi...
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WO/2016/030383A1 |
The invention relates to a method for producing primary amines, characterized in that at least one nitrile is hydrogenated in a device (V1) in the presence of a cobalt-based full contact catalyst while obtaining at least one primary amin...
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WO/2016/023837A1 |
The present invention relates to an amine of the formula (I) and to a process for its preparation by reductive alkylation of 1,2-propylenediamine with a di- or trifunctional carbonyl compound and hydrogen. The amine of the formula (I) is...
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WO/2016/023773A1 |
The invention relates to a method for producing 2,2-difluoroethylamine, wherein difluoroacetonitrile is used as starting material and the difluoroacetonitrile is hydrogenated with hydrogen at a hydrogen partial pressure of 2 to 25 MPa an...
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WO/2016/023913A1 |
A process for the preparation of a compound of formula (I) and of a acid salt (T) wherein R1 is selected from the group consisting of alkyl, aryl, cycloalkyl, heteroalkyl, heteroaryl and heterocycloalkyl, R2 and R3, are, independently of...
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WO/2016/020440A1 |
The present invention refers to a method for the synthesis of a compound of formula (I), solvates, stereoisomers or salts thereof, a key intermediate in the synthesis of Mirabegron by reduction of an amide in the presence of an amine-bor...
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WO/2016/016321A1 |
A process for the synthesis of Dapsone and intermediates thereof are described.
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WO/2016/013184A1 |
[Problem] To provide an organic electroluminescent element having high efficiency, low driving voltage and long service life by combining, as materials for an organic electroluminescent element having high efficiency and high durability,...
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WO/2016/014380A1 |
Liquid diphenylamine compositions comprising predominately p, p'-di-alkylated diphenylamines and low amounts of mono-alkylated diphenylamines are prepared by adding an olefin to a mixture comprising mono-alkylated diphenylamines, di-alky...
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WO/2016/004867A1 |
A process for the production of aromatic primary amines, by reacting an aromatic dialdehyde with hydrogen and ammonia or an ammonia-liberating compound, in the presence of a hydrogenation catalyst and an amine, wherein the molar ratio of...
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WO/2016/004771A1 |
The present invention relates to a continuous distillation casting device for an organic solid material, comprising a solid liquefaction vessel, a distillation vessel, a product collection container, an impurity collection container, a v...
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WO/2016/005269A1 |
The invention relates to a production process for polyamines through condensation of aromatic amines with formaldehyde employing at least one solid zeolite catalyst partially or fully ion-exchanged to the protonic form which has been A) ...
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WO/2016/002762A1 |
The present invention provides a novel iridium compound, a method for producing this compound, a catalyst including this compound, and a method for producing a primary amine compound by reacting an alcohol compound and ammonia in the pre...
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WO/2015/197527A1 |
The present invention relates to a process for preparing di- and polyamines of the diphenylmethane series (MDA), a system for producing MDA and a process for operating a system for preparing MDA. The invention enables optimization of pro...
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WO/2015/197519A1 |
The invention relates to a method for the preparation of di- and polyamines of the diphenylmethane series, care being taken during the shutdown of the production process that an excess of aniline with respect to formalin is ensured.
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WO/2015/197520A1 |
The invention relates to a method for the preparation of di- and polyamines of the diphenylmethane series (MDA) from aniline and formaldehyde, care being taken during the start up that a sufficient excess of aniline with respect to forma...
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WO/2015/200630A1 |
Phosphorus-containing ligands are recovered from mixtures comprising 3-pentenenitrile (3PN) and adiponitrile (ADN), using liquid-liquid extraction. ADN is produced by hydrocyanation of 3PN. The ADN is hydrogenated to produce a hexamethyi...
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WO/2015/192433A1 |
Provided is a process for synthesizing (R)-1-(naphthalene-1-group) ethylamine (I). The process comprises: using 1-acetonaphthone as a starting raw material; reducing the 1-acetonaphthone to (S)-1-(naphthalene-1-group) ethanol (II) by mea...
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WO/2015/189235A1 |
Method for reducing the concentration of nitrogen oxides in waste gases released during the production of organic amino compounds, wherein an organic compound is first reacted with NOx and/or nitric acid to form an organic nitro compound...
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WO/2015/188005A1 |
The invention relates to the preparation and characterization of novel salts of (R)-isometheptene and crystalline forms thereof; moreover, the invention describes the use of the novel salts alone or in combination with other therapeutic ...
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WO/2015/180485A1 |
The present invention relates to an amantadine nitrate compound having a neuroprotective effect and a preparation and a medical use thereof. The compound has the structure of the general formula (I). The compound has multiple mechanisms ...
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WO/2015/178847A1 |
There is provided a method for the preparation of an enantiomerically enriched amine by asymmetric hydrogenation of a prochiral oxime.
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WO/2015/178846A1 |
There is provided a method for the preparation of an enantiomerically enriched amine from a prochiral ketone.
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