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Matches 601 - 650 out of 73,208

Document Document Title
WO/2023/186945A1
The present invention relates to the cosmetic, nutraceutical use of a Lactobacillus crispatus strain and/or of a composition comprising same to decrease the pigmentation of the skin and/or of the mucous membranes and/or prevent the incre...  
WO/2023/192351A1
Described herein are methods and compositions for treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a ...  
WO/2023/192408A1
Disclosed are compounds of the formula (I): wherein R1-R5, X, Y1 and Y2 are as defined in the specification, pharmaceutical salts thereof and stereoisomers thereof, and pharmaceutical compositions containing one or more of these compound...  
WO/2023/186957A1
The present invention concerns an aqueous solution comprising molecular hydrogen and at least one salt, wherein said solution has an ionic strength in the range from 0.001 mol/l to 1 mol/l and comprises ascorbic acid or a salt thereof. T...  
WO/2023/184114A1
The present application provides a polypeptide and a cosmetic composition or pharmaceutical composition and use thereof. The polypeptide has the following general formula: R1-X1-X2-X3-X4-X5-X6-X7-X8-R2. The present application relates to...  
WO/2023/191204A1
The present invention relates to a peptide composition having angiogenic activity, and a pharmaceutical composition using same and a cosmetic composition using same. The peptide forms a hydrogen bond with nicotinamide mononucleotide, whi...  
WO/2023/190826A1
The present invention relates to a pharmaceutical composition for preventing, suppressing, or treating the symptoms that accompany pseudo-allergic reactions, said pharmaceutical composition comprising, as an active ingredient, a compound...  
WO/2023/191016A1
This fibrillin production promoter contains a pyrimidine nucleotide or a precursor thereof as an active ingredient.  
WO/2023/191196A1
The present invention relates to a composition for reducing skin photoaging, comprising Pediococcus acidilactici LM1013 (KCTC12039BP) as an active ingredient. The composition for reducing skin photoaging, comprising Pediococcus acidilact...  
WO/2023/184986A1
The present invention provides use of a CD36 inhibitor in preparing a medicament for inhibiting scarring after spinal cord injury. The present invention relates to the field of biotechnology, and particularly to use of a CD36 inhibitor i...  
WO/2023/189035A1
A composition according to the present invention contains, as active ingredients, the following components (1), (2), (3), and (4). Component (1): At least one herbal medicine selected from the group consisting of Ligustrum fruit, yerba...  
WO/2023/185638A1
A crystal form of a quinoline derivative and a preparation method therefor. The crystal form of a quinoline derivative has good stability, fluidity, compressibility, solubility, bioavailability and the like, so that a wide selection of a...  
WO/2023/191665A1
The invention relates, in particular, to monoclonal antibodies that specifically bind to an alpha chain of the receptor to human interleukin 4 (hIL-4Rα) and have reduced immunogenic activity as compared with an antibody dupilumab, which...  
WO/2023/191515A1
The present invention relates to a composition for preventing hair loss or promoting hair growth, comprising an indirubin derivative and a metabolic activator. The composition, according to the present invention, may be effectively used ...  
WO/2023/189321A1
Provided are: an atopic dermatitis ameliorating agent comprising a glyceryl ascorbic acid acylated derivative having a specific molecular structure; etc.  
WO/2023/187198A1
The present invention relates to the use of the HIP/PAP protein, or a derivative thereof, for treating and/or preventing, in an individual in need thereof, a disorder characterized by a CXCL5 level higher in a biological sample of said i...  
WO/2023/190518A1
The present invention inhibits oxidative stress. An oxidative stress inhibitor that comprises a compound represented by general formula (I) or a salt thereof exclusively as an active ingredient. (In the formula, R1 to R9 are the same or ...  
WO/2023/190117A1
The present disclosure addresses the problem of providing a method for producing a new ellagic acid-containing composition capable of improving solubility of ellagic acid. The present embodiment is a method for producing an ellagic acid-...  
WO/2023/182856A1
The present invention relates to a pharmaceutical composition and a skin topical composition, each including a Rho-kinase inhibitor as an active ingredient for the prevention or treatment of skin fibrotic disorders, and a method for the ...  
WO/2023/180576A1
The invention relates to pharmaceutical matrix tablets for oral administration comprising a bradykinin B2 receptor antagonist having a chemical structure according to Formula (1), or a salt or solvate thereof, wherein R is deuterium or h...  
WO/2023/182579A1
The composition comprising potassium all-trans retinoate (PATRA) for inhibiting skin inflammation in acne and photoaging patients having high levels of inflammatory proteins and residual skin components secreted from the skin exhibits hi...  
WO/2023/182192A1
The objective of the present invention is to provide a composition which is for inhibiting Pseudomonas syringae, contains alcohol, and can inhibit the growth of Pseudomonas syringae while inhibiting the production of IL-1α caused by the...  
WO/2023/180661A1
The present invention relates to the novel cosmetic or dermatological use of an extract of Dendrobium officinale and/or of a composition comprising same for maintaining and/or increasing the thickness of the skin, preferably of the epide...  
WO/2023/180564A1
Biocompatible antiseptic composition containing 9-hydroxycalabaxanthone and/or related xanthones The present invention relates to a cosmetic or pharmaceutical composition containing 9-hydroxycalabaxanthone in the form of gel, aqueous sol...  
WO/2023/181563A1
Provided is an anti-adhesive material containing particles, in which the particles comprise a crosslinked product of a gelatin mixture composed of a first gelatin and a second gelatin having such a structure that a hydrocarbon group is i...  
WO/2023/183396A1
Provided herein are methods and compositions related to Prevotella bacteria useful as therapeutic agents, e.g., for the treatment of inflammatory disease.  
WO/2023/178592A1
Disclosed herein is a method of treating diseases and/or disorders associated with the dysregulated activation and recruitment of neutrophils. The method includes administering to a subject in need thereof an effective amount of an extra...  
WO/2023/179905A1
The present application relates to a combination of 5-amino-2,3-dihydro-1,4- phthalazinedione or one of its pharmaceutically acceptable salts and at least one fumaric acid ester or a pharmaceutically acceptable salt thereof. In particula...  
WO/2023/178861A1
Provided in the present invention are the use of platelet-derived growth factor in preparation of a medicine for treating burns and scalds. When being used to prepare an external application preparation for treating burns and scalds of a...  
WO/2023/180281A1
The present invention refers to peptides which provide for the protection of telomeres, antioxidant and anti-inflammatory activities and, hence, are useful in cosmetics for the prevention, reduction and/or treatment of inflammaging and s...  
WO/2023/180575A1
The invention relates to solid dispersions for oral administration comprising a bradykinin B2 receptor antagonist having a chemical structure according to Formula (1), or a salt or solvate thereof, wherein R is deuterium or hydrogen: For...  
WO/2023/183059A1
The present invention provides a method of treating pathological inflammation in a patient comprising: administering to the patient a multivalent structured polypeptide comprising at least one therapeutic peptide. The present invention a...  
WO/2023/181755A1
Provided is: a highly-safe and low-cost expression regulator for a factor particularly involved in maturation, moisture retention, or barrier function of the skin; an expression enhancer for an antimicrobial peptide; an expression enhanc...  
WO/2023/182468A1
The present disclosure provides a wound treatment composition and the like. N-(\{2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-ox azol-4-yl\}methyl)-2-ethoxybenzamide or a salt thereof is useful as an active ingredient of the woun...  
WO/2023/180214A1
The invention relates to compositions, particularly topical compositions comprising a urolithin, cosmetic compositions comprising a urolithin and cosmetic compositions comprising a urolithin and trehalose, compositions comprising urolith...  
WO/2023/183901A1
Compounds, compositions thereof, and methods of using the same in dosing protocols for the inhibition of TYK2, and the treatment of inflammatory disorders including psoriasis and psoriatic arthritis are described.  
WO/2023/114833A9
The instant disclosure provides selective Treg stimulator compositions, including RUR20kD-IL-2 and related compositions, and rezpegaldesleukin, and formulations and dosing regimens for methods of using these compositions, for example, fo...  
WO/2023/174447A1
Disclosed are a mesenchymal stem cell wound repair dominant functional cluster (Hr-MSC), identification thereof, and an application. The mesenchymal stem cell wound repair dominant functional cluster has a biomarker combination comprisin...  
WO/2023/178219A1
The present disclosure concerns use of activated or inactivated fibroblasts or fibroblast-derived materials, such as exosomes from fibroblasts, for wound care. The methods and compositions are useful for purpose of tissue differentiation...  
WO/2023/174205A1
The present invention relates to a pharmaceutical formulation and use thereof, belonging to the field of pharmacy. The pharmaceutical formulation has significant effects in preventing and treating renal diseases, eye diseases, ulcerative...  
WO/2023/178256A1
The present disclosure relates to methods for treating plexiform neurofibromas associated with neurofibromatosis type 1 (NF1-PN), comprising administering to a pediatric patient (e.g., 2 to 15 years of age) in need thereof mirdametinib o...  
WO/2023/177207A1
The present invention relates to a scalp or hair care composition comprising a nano-carbon structure, and the nano-carbon structure of the present invention can retain moisture of the scalp or hair even in a small amount, and relieve inf...  
WO/2023/178099A1
Described herein are NLRP3 modulators and methods of utilizing NLRP3 modulators in the treatment of diseases, disorders or conditions. Also described herein are pharmaceutical compositions containing such compounds.  
WO/2023/176952A1
The purpose of the present invention is to provide a means for controlling the proliferation of a bacterium in the intestine. Provided is a composition for controlling the proliferation of any one bacterium selected from the group consis...  
WO/2023/176951A1
Provided is a means for controlling proliferation of Collinsella bacteria in the intestines. The present invention addresses the problem of providing a novel material that is capable of controlling proliferation of Collinsella bacteria. ...  
WO/2023/177625A1
Disclosed herein are shelf-stable formulations comprising benzoyl peroxide in a formulation effective to reduce or prevent degradation of the benzoyl peroxide to benzene. Further provided herein are methods of preventing or reducing degr...  
WO/2023/178269A1
The present disclosure relates to methods for treating cutaneous neurofibromas (cNF) comprising administering to a patient in need thereof mirdametinib or a pharmaceutically acceptable salt thereof.  
WO/2023/174981A1
The present invention relates to an aqueous extract obtained from a plant of the genus Aster for cosmetic or therapeutic applications, in particular in the prevention and/or treatment of acne.  
WO/2023/174039A1
Disclosed herein are anti-MASP-2 antibodies and antigen-binding fragments, polynucleotides encoding the antibodies and antigen-binding fragments, and pharmaceutical compositions comprising the antibodies and antigen-binding fragments. Us...  
WO/2023/176796A1
The problem to be solved by the present invention is to provide a novel scar formation inhibitor having, as an active ingredient, a compound that has not been conventionally known to have an effect for inhibiting scar formation. The pres...  

Matches 601 - 650 out of 73,208