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WO/2011/063940A1 |
The present disclosure relates to a continuous process for selectively modifying the lumen surface of a hollow fiber membrane using a plasma, an apparatus for carrying out the process and to hollow fiber membranes obtainable by the proce...
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WO/2011/060554A1 |
The present description relates to a presolidified implant composition, a method for its preparation, and a use of said implant composition for repairing tissue of a patient wherein the implant comprises a blood component, a salt and a p...
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WO/2011/059123A1 |
The present invention relates to a heparin compound bound to an adhesive material, a preparation method thereof, a solid surface coating agent containing the same as an active ingredient, and a coating method of a solid surface using the...
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WO/2011/006507A2 |
The present invention relates to preparation of a polymer coating comprising or consisting of polymer chains comprising or consisting of units of 2-methoxyethyl acrylate synthesized by Surface-Initiated Atom Transfer Radical Polymerizati...
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WO/2010/150874A1 |
A surgery instrument which can be used for both general surgery and endoscopic surgery and consists of a material having not only liquid-absorbing properties and liquid-retaining properties but also excellent liquid removal properties. T...
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WO/2010/123465A2 |
The subject of the invention is a method for the treatment of biomedical implants for the improvement of antithrombogenic properties thereof. The mentioned biomedical implants are cardiovascular implants, especially artificial blood vess...
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WO/2010/118335A1 |
Methods for protecting biomaterĪals comprise attaching CD47 or Ig domain thereof to the surface of the biomaterial, thereby inhibiting or reducing immune cell attachment and/or immune cell-mediated damage to the biomaterial. Also provid...
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WO/2010/113632A1 |
Disclosed is a surface-treating agent characterized by comprising a copolymer composed of, as monomer components, a monomer (A) having a hydrophilic functional group and represented by formula (1) or (2),a monomer (B) having a basic func...
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WO/2010/090097A1 |
Disclosed is an antibacterial catheter (1) which is characterized by comprising a tube-shaped main body (2) composed of a polymer material containing an antibacterial agent (3), wherein the antibacterial agent (3) is localized in the vic...
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WO/2010/057142A2 |
The present invention provides compositions and methods for the production of silk fibroin matrices surface-PEGylated on one or more surfaces. Such surface-PEGylated silk fibroin matrices can be used in biomedical applications, such as a...
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WO/2010/026782A1 |
Previously reported composite materials each of which is composed of a hydrophilic high-molecular-weight matrix and a low-molecular-weight organic compound have such a problem that it is difficult to compound a low-molecular-weight organ...
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WO/2010/009335A1 |
Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on said substrate, wherein said coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable ...
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WO/2009/119761A1 |
Provided is a surface showing excellent antithrombotic properties. Also provided is a medical device having the same. An antithrombotic surface comprising polymer layers which are in different charged states and alternately layered, char...
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WO/2009/110858A2 |
The present invention is directed to medical devices in which flow is channeled of blood and blood products for the purpose of effecting a chemical exchange to remove desired chemicals from the blood or blood products, and to impart nitr...
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WO/2009/089364A2 |
An optical fiber tip comprises a core and a recess formed in said core at a distal end of the optical fiber tip, said recess having a vertex within said core.
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WO/2009/081870A1 |
Disclosed is a medical device having excellent anti-thrombotic properties, excellent sliding properties, and an inhibitory effect on cell adhesion. The medical device comprises: a base on which a hydroxy group can be formed; and a biocom...
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WO/2006/130150A9 |
Graphitic nanotubes, which includes tubular fullerenes (commonly called "buckytubes") and fibrils, which are functionalized by chemical substitution or by adsorption of functional moieties. More specifically the invention relates to sing...
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WO/2009/064372A2 |
The present invention relates to immobilized biologically active entities having heparin cofactor Il binding activity.
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WO/2009/065087A1 |
An automated apparatus and method for coating medical devices such as an intravascular stent, are disclosed in the method, a 2-D image of a stent is processed to determine (1 ) paths along the stent skeletal elements by which a stent sec...
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WO/2009/058146A1 |
The present invention is directed to medical devices including blood storage and handling products that comprise a specific polyphosphazene and the capability of releasing nitric oxide or other smooth muscle relaxant compounds in vivo or...
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WO/2009/049426A1 |
The invention features the use of a matrix consisting of low molecular weight components for use as a self-eliminating coating for implantable medical devices. The matrix coatings can be used to enhance biocompatibility and to control th...
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WO/2009/048314A1 |
The present invention provides implantable receptacle devices (and methods) for use in bone and tissue regeneration which provide immediate structural stability and strength to a zone where tissue regeneration is required. By virtue of t...
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WO/2009/045454A1 |
Implantable catheters treated with gentian violet and methods for disinfecting the catheters with alcohol are provided.
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WO/2009/035457A1 |
A dip coating apparatus and method of dip coating. The apparatus includes a guide surface, a bendable tube, a carriage, and a support assembly. The bendable tube redirectionally engages the guide surface intermediate the first and second...
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WO/2009/031295A1 |
It is intended to provide a stent and a method for producing the same. The stent comprises a cylindrical stent main body having an outer surface and an inner surface, a first coating layer which coats at least the outer surface of the st...
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WO/2009/018325A1 |
A method, a kit, and an apparatus provide a coating on an implantable medical device. The apparatus includes housing, a sealed reservoir chamber disposed in the housing, a reducing template, and a reservoir access port. The sealed reserv...
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WO/2009/005258A2 |
Heparin conjugates and methods of making and use thereof are disclosed. An illustrative heparin conjugate includes a composition wherein a bile acid is bonded to heparin through the 3-carbon of the bile acid. A spacer may be interposed b...
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WO/2007/143609A9 |
Metallic stents are treated with a gaseous species in a plasma state under conditions causing the species to polymerize and to be deposited in polymerized form on the metallic stent surface prior to the application of a drug-polymer mixt...
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WO/2008/156604A1 |
A method of providing a biocompatible PEG-comprising coating on a substrate, without the use of an underlying adhesion layer. The coating is vapor deposited onto the substrate from a precursor which includes a PEG-derived moiety and an a...
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WO/2008/144130A2 |
The present invention relates to implantable medical devices coated with phosphoryl choline acrylate polymer topcoat layer, an acrylate copolymer layer containing a therapeutic agent, and their use in the treatment of vascular diseases.
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WO/2008/134575A2 |
The present invention provides an apparatus and a method for modifying a structure such as a medical device through the selective application of a coating. A coating sleeve may comprise an elastomeric wall that may be permeable or imperm...
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WO/2008/131131A1 |
Provided herein is a coated coronary stent, comprising:. a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer an...
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WO/2008/123108A1 |
Disclosed is a medical device intended to be placed in a living body, which comprises a base body having a desired shape and a physiologically active substance release layer formed on the surface of the base body. The physiologically act...
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WO/2008/118538A2 |
Embodiments include polymeric coatings formed from poly((perfluoro)organo)phosphazene-based materials. The coatings may be utilized to coat any suitable substrates, and in some embodiments may be utilized to coat surfaces of medical impl...
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WO/2008/117644A1 |
The invention aims at providing a low-cost coating composition which can inhibit the adsorption of biorelated substances and is excellent in water resistance and strength; and usage thereof. The coating composition is characterized by co...
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WO/2008/104528A2 |
Implantable materials for medical or surgical applications comprising specific chemical groups on their surface to alter the physico-chemical properties of said material rendering it suitable implantation or biocompatible properties.
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WO/2008/068531A2 |
There is provided a biomaterial having a functionalised surface which comprises bi-functional semi-dendrimers. The biomaterial may be ceramic, metallic and/or polymeric. It will usually be in the form of a solid, but could be a semi-soli...
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WO/2008/068868A1 |
It is intended to provide a surface treatment agent which is more excellent in antithrombogenicity, and consequently biocompatibility, compared with conventional medical materials and has high hydrophilicity. Further, it is intended to p...
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WO/2008/063157A2 |
A method for preventing or treating a blood clotting disorder is disclosed. The method includes administering a therapeutic effective amount of at least one nanoparticle-based anticoagulant to a subject afflicted with blood clotting diso...
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WO/2008/059975A1 |
The invention provides a blood-coagulation inhibiting material which has excellent stretchability and little influence on the living body and can inhibit blood-coagulation efficiently. The material is a multi-block copolymer comprising s...
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WO/2008/054965A2 |
The composition of matter includes an alloy formed by vaporization of either magnesium or iron in continuation with one or more metals. This results in an array of alloy members each making up the alloy and extending from a base to an up...
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WO/2008/052000A2 |
A stent holder for mounting and electrically charging a stent during coating of the stent using dry particles, the particles comprising inert polymers, pharmaceutical or biological agents, is provided. An assembly for supporting and elec...
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WO/2008/046630A1 |
A device for monitoring a parameter of a fluidic sample by microdialysis, the device comprising a permeable membrane, wherein the permeable membrane has a first surface to be brought in contact with the fluidic sample to traverse the per...
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WO/2008/039382A2 |
The present invention relates to products, methods, and processes of various ammonium salts and their use as anti-coagulants.
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WO/2008/037028A1 |
Biocompatible materials suitable for use in vascular applications have been engineered, combining human recombinant tropoelastin with other synthetic or natural biomaterials to form protoelastin. The materials can be in the form of elast...
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WO/2008/032758A1 |
Disclosed is a substrate containing a compound having an anticoagulating activity on the blood and a hydrophilic polymeric compound, wherein the amount of the compound having an anticoagulating activity on the blood eluted from the subst...
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WO/2008/032400A1 |
A method of introducing a compound having a blood anticoagulant activity unstable to radiation rays in a substrate surface by exposure to radiation rays to thereby modify the substrate surface, in particular, a relevant process for produ...
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WO/2008/030174A2 |
The present invention deals with the use of alkaline chemically bonded ceramic systems based on Ca-aluminate as a thrombogenecity reducing coating material. The invention is especially intended for coating of devices used in the human or...
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WO/2008/029744A1 |
Disclosed is a highly polymerizable diamine compound containing a phosphorylcholine group. Also disclosed is a high molecular weight polymer which uses the phosphorylcholine group-containing highly polymerizable diamine compound as one o...
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WO/2008/024514A2 |
A central venous access device comprising an extruded catheter shaft having one or more lumens, said catheter shaft comprising a polycarbonate polyurethane having a weight average molecular weight in excess of 90,000.
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